Son took Prilosec for 5 years. No one told us about acid rebound or that is was extremely hard to get off of. We tried 4 times over 2 years to get him off this med. Finally did it but it took time and many steps. What we did was very very slowly decrease the dosage. Eventually I would open the capsules and remove some of the little white balls inside to reduce the dosage more and more each week. After about 2-3 months we then switched to H2 blockers over the counter. Then after about 4-6 weeks we switched to Pepcid Complete….then slowly tapered off the amount he would take….and the last step was switching to only Mylanta…and then slowly reducing the dosage and frequency. I also gave him some natural supplements from the vitamin shop: glutamine (to soothe and protect the stomach lining), DGL licorice, aloe vera juice, mastic gum, and sulforaphane (broccoli extract). The key for us was to go very slow as you taper.