Well said!!! I, too, was terrified of the side effects of taking biologics for Ulcerative Colitis, and resisted until the UC became "fulminant" and I was advised to see a colorectal surgeon. Taking biologics was the last step before a colectomy so I started Entyvio in July 2019. Entyvio has been FDA approved for Crohn's and Ulcerative Colitis and it has a better safety profile than some of the other biologic drugs out there. I am happy to say that I have been in remission about 4 months and I believe it is not just the Entyvio. I started a plant based diet a couple weeks before starting the Entyvio and believe the combination is working! I, too, hope to stop taking it at some point and rely on just the plant based diet. I am not at that point, however, after only being on the biologic since July. I have discussed this with my GI doctor and while he supports the plant based diet, he said that there is no de-escalation data when stopping Entyvio, as it has only been FDA approved since 2014. So, we will revisit that in about a year, depending on how I'm doing and responding to the infusions. All I am doing is the Entyvio and the diet – no steroids, no anti-inflammatory drugs. I take the probiotic VSL#3, calcium, and a good multivitamin. You're right in saying that taking the drugs, while being closely monitored, is less scary. In fact today, I had my scheduled infusion and happened to be next to a woman that had been on Entyvio for 3 years to treat her Crohn's disease and she said it was life changing for her. It was so comforting to meet someone on Entyvio! We talked while having our infusions about the drugs, diet and how these conditions have changed our lives. We are both grateful that we are responding to the same drug, have an excellent GI doc and are feeling better now than we have in years! So, I agree that there absolutely is a place for these drugs in treating IBD, and I also agree that a dietary approach is just as important. My personal long term goal is to rely on the plant based diet and no longer need the drugs. One day at a time….