My update, I've been off pristiq since Sunday, February 24th, 2019. Today has been my best day to date. Anxiety lessened, no brain zaps or dizziness. I've been able to control the irratibilty throughout the day. I watched something on netflix last night after a particularly stressful day full of anxiety. It was called "Heal" about the powerful connection between the human psyche and physical health. This morning as soon as I woke up, I told myself I was going to control and conquer today and the anxiety that may come my way. I did. While my bloating and constipation are still off, I'll continue to take my vitamins and eat right until that area repairs itself. But the important point is that I feel better and myself again. My best advice is not to give up, to wean off slowly, lowering doses every three or four weeks. Every other day worked for me, but I have heard it's not the best way for your body. Also, have another medication to take temporarily while you are weaning off to help with the adverse effects. But you can do this. You will get off and be pristiq free. I'd been on it since October 2015, so about 3 1/2 years. It is possible to stop.