I am so sorry for what your wife has gone through. My autoimmune disease Errosive Lichen Planus I have had is best treated in University hospital and specialists in those areas. I’m starting my 5th decade. I get better and then have flares. If your HMO cannot diagnose you’re wife’s problems and they appear very sever perhaps asking for a referral to A large medical teaching hospital will help. Most will require all her medical history. My very best wishes for a remission. I know how frustrating these autoimmune diseases are. I have good years and bad years and frustration continues, but their are medical people who care!