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Thu, Nov 7 5:58pm · Pudendal Nerve Entrapment/Neuropathy/Damage in Chronic Pain

@teg and @vklittle61 EXACTLY! If you are able get on the nattokinase and serrapeptidase and higher levels of vitamin C and also add quercetin and resveratrol as supplements. I basically had a bursitis / tendonitis in the glute and high hamstring region. It was stubborn. However, I believe it was from excessive fibrin (i.e. the protein involved in blood clotting) on the bursa / tendons & nerves. I had nerve pain (nerve compression; some type of myofascial pain in the glutes, and all manner of sitting pain). While speculative, the fibrin might cause not only stiffness but promotes inflammation as it naturally recruits white blood cells (granulocytes) that promote a mild autoimmune inflammation of the tissues. This is a natural process for fibrin- essentially what happens in a cut or wound – but it may be more prevalent for that process to go haywire – especially as we age. The enzymes (nattokinase / serrapeptidase) can help reverse this – a small amount is actually absorbed somehow.

I also had a prior history of plantar fascitis and also phlebitis (and pain when pressing on lower legs). This is all consistent with tissue stiffening. As you may be aware, many people are eventually put on anti-coagulants by Western medicine due to forming clots / fibrin deposition – which may be more common with age and improper healing / tissue remodeling. The enzymes and Vitamin C and stretching & exercise took care of much of it for me – I only have a little residual sitting pain now. I believe what I had could have led to many different issues including amyloid polyneuropathy (eventually) and possibly other related disorders (other neuropathies) – had I not intervened with the alternative treatments (I was getting burning and tingling down in my left foot – that is now lessened). NSAID's don't help this and that is what Western medicine tries. The stiffness and irritation can definitely cause nerve compression and nerve irritation leading to burning pains, spasms, etc., and sitting pain.

The enzymes are taken on an empty stomach (i.e. between meals). About 10% of the people get digestive issues. Most people have no
problems with the enzymes, though. You'll need to listen to your body. I've used: 2000 U nattokinase (Drs. Best in both am and pm) as well as a couple Serrapeptidase (Biomedix Laboratories brand; several different strengths are available in the am and pm, too) from Amazon. There is also a stronger enzyme called Lumbrokinase, too. Start slow and ramp your way up. See how it goes. My doctor checked and if you have a bleeding disorder or are already on anti-coagulants they might be counter indicated. Otherwise, barring you have a clotting disorder or if you have an infection (discontinue during an active infection; as infections are often walled off by fibrin). Many people use these without issue and my doctor found little information – but not much for adverse effects, either. Most likely, these enzymes are safer than Warfarin and other anti-coagulants. I am convinced the enzymes and the other supplements I mentioned above helped "cure" me of my sitting pain which maps to the pudendal and other interconnected nerves, too. At least, that was my case. I am 100% convinced about my fibrin hypothesis – for me at least. Your cause may be different – or maybe not.

In the meanwhile, there are old posts from me on here (old posts on this thread) or on the "Pain in the butt – Can't sit down" thread under chronic pain where I detailed specific cushions I used, etc., and all manner of specifics about exercise before the resolution of the sitting pain. You can look them up. While some nerve pain meds help – they won't cure the problem – they just mask the pain. Maybe for you, the enzymes as well as some pelvic floor therapy and some of the specific exercises I'd mentioned before might cure your issue. Please do your own research and fact checking. Be sure to check your blood pressure when on various supplements. They might affect it either raising or lowering it. Good Luck. Rich

Mon, Oct 28 7:47am · Has anyone been diagnosed with Abdominal Wall Pain in Chronic Pain

There is a $10.00 book called “life after pain” by Dr. Jonathan Kuttner. He discusses pain sensitization and also has some online courses where you can retrain your pain system. It works for many.

One more question: have you tried the enzymes nattokinase and serrapeptidase? They may help scar tissue remodel which can cut down on nerve compression which is often the cause of pain. Along with vitamin c, quercetin, resveratrol and stretching and exercise I got rid of a lot of myofascial pain thanks to the package of supplements- but especially the two enzymes. Those are taken on an empty stomach.

Wed, Sep 18 12:16pm · Bowel incontinence in Digestive Health

@kzsolheid I get Harvard Health newsletter and they just had an article about this. I'm not sure what type of physical therapy you had, but a pelvic floor specialist might help. Also, in the newsletter they referenced various treatments including electrical stimulation, etc., which may increase muscle tone or somehow help. Keep trying – maybe it can be made better. Have you seen a neurologist, too, or the gastroenterologist, etc.? Just some questions for you to think about.

Wed, Sep 18 11:59am · Stiff Person Syndrome in Brain & Nervous System

@trs Just curious have you tried enzymes serrapeptidase (Biomedix Labs) and nattokinase (Drs. Best)? I had a lot of stiffness in whole regions of my body and over time it subsided. My thinking was, deposits of fibrin / other proteins may have irritated nerves. These enzymes may help get rid of these "adhesions". It worked for me. Got rid of plantar fascitis, phlebitis, and general glute stiffness. Just wondering. The counter-indication is if you are on blood thinners already or have a blood disorder. Otherwise, these might be worth a try. PM me if you want more specifics.

Sun, Sep 8 10:21pm · Pudendal Nerve Entrapment/Neuropathy/Damage in Chronic Pain

@teg These are strictly alternative medicine. However, there was a Japanese Pharmaceutical company called Takeda that sold it for many years. They discontinued as for the conditions they marketed Serrapeptidase it was not more effective than placebo. It wasn't a big part of their revenues. For purposes of clearing blood vessels of plaques and possibly helping tissues remodel, these may be very useful. Check out Serrapeptidase from Biomedix labs and Nattokinase from Doctors best on Amazon. Read the reviews and see what you think from people who use these. They helped me, I believe.

Sat, Sep 7 9:24am · Pain in the butt - Can't sit down in Chronic Pain

@ailean55 I have all those indications on my MRI’s including lower lumbar DDD, hip arthritis, torn labrum cartilage on both sides , but not fibromyalgia. However, I found I was able to get rid of almost all my pain with stretching, exercise and the right supplements including serrapeptidase and nattokinase enzymes. Some hemp seed oil (I. e. Healthy fats) cut pain and I also take some resveratrol / quercetin / turmeric, a small amount of rutin & multivitamins extra vitamin c to the maximum recommended level and some extra magnesium. Be sure to check blood pressure as some supplements can make it go up or down and don’t use the enzymes if you are already on anticoagulants or have a bleeding disorder. I have several posts where I described specific exercises I do either in this thread or in the pudendal neuralgia thread. The enzymes were a game changer for me and my muscles started feeling less ropey with less scar tissue after 2-3 months. Then you can cut back on the enzymes (but to work properly I do believe you need to stretch and exercise (or walk)) some for best results. At least, that was my experience. Now I have much less sitting pain and much less stiffness from myofascial pain. PM me if you want a detailed protocol beyond the list I gave you.

Fri, Sep 6 9:28am · Pudendal Nerve Entrapment/Neuropathy/Damage in Chronic Pain

@resawaller Have you tried serrapeptidase and nattokinase enzymes? These may be able to aid in scar tissue remodeling and possibly reduce nerve compression (along with stretching and exercise). I believe I posted about these in this thread and possibly in the pain in the butt thread here under chronic pain topic. These helped me a lot, I think.

Sun, Sep 1 11:40pm · Pain in the butt - Can't sit down in Chronic Pain

@schony1087 there is a long thread with many comments in this section and also in the "pudendal nerve entrapment" thread of chronic pain. There may be some suggestions there that will help you. Unfortunately, those looking for a quick fix via surgery generally are not pleased to find out that due to the highly vascular and innervated area, surgery is often not an option. In fact, you're indicating surgery may have caused an issue. However, the areas are soft tissue and stretching, exercise, the right meds and supplements for pain and the right type of body work (ultrasound / myofascial techniques, etc.) might help you out tremendously. I've made quite a few detailed posts myself. My pain has gone way down over time so it can get better. Please look over those two threads extensively.