@patts When you do a pulse a taper, it's a way of weaning you off the drug and hope more "good" bacteria will grow. You may now be taking 2 or 3 Vanco a day and when you taper, you may go to 1 or 2 and day for one week and then it will be cut to one a day…. and in my case, I even went to 1 every other day. However, two weeks after doing that, the Cdiff returned. As a last resort, I took Dificid which is highly expensive. I had made the decision that if the Dificid did not work, I would do the FMT.