Is the allogeneic donor related? Either way, it is a long road. Your son will become weaker and sicker with the chemo designed to kill off his existing bone marrow. Once he receives his donor cells, he will begin his climb back, very slowly. The biggest risk during the entire time his infection, followed by a graph versus host disease. He will be monitored extremely closely, with bloodwork every day. I was hospitalized for four weeks for my transplant, but some centers don’t require that. Your son will be very very tired, have a little appetite, and have side effects like mouth sores, swelling from the steroids, and some, but not all of the predicted complications. Once he’s well enough to go home, it takes many months to regain strength and return to normal activities. Sometimes graph versus host disease continues to be a problem and requires follow-up from your local center. Little by little he will regain his strength, but to become 100% can take quite some time. Please let me know if you have any specific questions. Warmest regards and best wishes.