I have had Erythema Nodosum for over 7 years. Its chronic and never goes away fully. As soon as some of my knots heal, others form. I run fevers almost daily and have no energy. The pain is something I have learned to live with but life is very frustrating because of EN. I currently take Celebrex and it has given me some energy back but my knots are worse now than they’ve been in a long time. I have been tested a million times for different things with no luck. The most frustrating part of this is that nobody can relate and not many people understand because I don’t look sick. I wish I had the answers for this but it seems like there are no answers.