Hi Colleen. I am currently on Vectibix while at the hospital and then go home with an infusion pump that infuses 5-FU over the next 46 hours. Then I get to disconnect. Since my treatments began in 2011 I've been on all the chemo drugs known to treat cMRC yet the nodules continue to grow. Thank God their not spreading. Once the cancer has become immune to one drug they switch to another. The Vectibix is my last hope. After that all I have left is clinical trials. I've been very lucky over the years with really no side effects at all. No nausea, no diarrhea, my hair fell out naturally so nothing there. Back in the beginning I got neuropathy in my hands and feet from I think Oxiplatin? Doctor changed drugs and after a few years it's more or less gone away. Living with cancer has certainly been a challenge. It's the having to go for chemo every other week that sometimes gets to me. No long vacations are ever in my plans. I am so blessed God put my wife, and caregiver, in my life. Without her and her support and positive attitude I'm sure I wouldn't be writing to you today. She has been through it all with me. Never even missed not one of my appointments. A true Earth Angel sent by God to look after me.