Hi there, you have been given wonderful information on this site but I haven’t heard much on your son’s level of comfort. I suffered an extreme traumatic brain injury 7 years ago, I have and do experience symptoms similar to your son’s and I am a nurse. Please be advocate for your son and his level of comfort. What has worked well for me is medical marijuana. There is a very wide range of flowers that manage pain, and do not affect me mentally. This treatment option had also proven effective in managing seizure activity. Best of luck!