I think we all understand how you are feeling about Prednisone and it's side effects. I now have osteoporosis and have to get a shot (Prolia) every six months. I'm also having a terrible time weaning down off of Prednisone. I started at 40 mg. and have been trying to wean down for well over a year. I actually got down to 1 mg., which was a big tease because I relapsed and basically had to start over. Last week, my dosage was upped from 3 mg. to 5 mg. because I was beginning to relapse again, and I have been told to stay on this dosage until I have been in remission for 4-6 weeks before we begin to fiddle with daily dosage amounts again. I'm also on 200 mg. of azathioprine and 20 mg. of tamoxifen daily. I am also on CBD oil as well. For nausea, I take Ondansetron (4 mg.) as needed. Also, as needed for pain, I am on oxycodone and a different pill in the family called Targin (I'm from Canada, so this might be a different name for my American cousins!) which is a slow release milder pill that has an anti constipating agent in it, I believe. This bout has been very difficult and I have been battling this relapse since August 2017. I wanted you to know all of the meds that I am currently taking, so that you may discuss options with your doctor and I hope that this information will be helpful. I have learned that this disease presents itself differently for all of us, but there are many similarities for sure! I experience good and bad days and am noticing that the weather (April and November are typically tough months!) and stress (or upset) are major factors in my pain level. Some people notice that a change of diet can be helpful as well. I hope this info helps you. You are definitely not alone.