Badges (1)

About

Member has chosen to not make this information public.

Groups

Member not yet following any Groups.

Pages

Member not yet following any Pages.

Posts (10)

Nov 9, 2017 · FGFR3 ANTIBODY in Neuropathy

Darlia, that is a very informative article- thank you! I feel (like John) that I wish I could point you in the right direction for some relief and recovery. ;-( ~Laurie

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

I was just thinking about the radiation/chemo agent link to neuropathy and it got me to wondering about those who have taken gadolinium, the agent use for MRI’s that is linked to neuropathy: https://gadoliniumtoxicity.com/2014/10/25/pain-from-peripheral-neuropathy-can-be-caused-by-metals-like-gadolinium/

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

Oops, through more searching I am now seeing that on one of my husband’s records, it says he has FGFR3 associated small fiber predominant polyneuropathy.

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

Very helpful- I need to get the numbers on my husband’s blood work. It was also done at WashU.

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

You’ll have to get referred to a neurologist for testing- that’s what my husband had to go thru once his symptoms starting.

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

Great find- that explains a lot.

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

My husband has Radiation-Induced Peripheral Neuropathy (RIPN), Radiation-Induced Brachial Plexopathy (RIBP) and Chemo-Induced Peripheral Neuropathy (CIPN). His neurologist just mentioned in his medical report that the FGFR3 showed up in his blood work. He didn’t call it FGFR3 Neuropathy. From what I know, neuropathy is directly caused by radiation or chemo given in as a cancer treatment. In chemotherapy treatment, the chemo agents, Cisplatin or Cipro, cross the brain barrier. In radiation, it damages the nerves as well.I called the tech support for the manufacturer of the FGFR3 antibody that is manufactured from rabbit genes and it is made specifically for research only, not to be sold by to a third party. However, I found clinical trials using it for cancer treatments (which must be how my husband got it, although that was back in 2008). FGFR3 blocks peptide PEP-1617, which is necessary for bone growth, and can be manufactured ‘normally’ as an antigen in our own bodies to attack this peptide (but to me, that would mean it is now an auto-immune issue) but high levels in the blood would be suspicious, or it can be made synthetically in a lab and delivered to the body to fight off cancers and other things relating to growth (even though the manufacturer is not condoning its use except for research purposes).

Nov 8, 2017 · FGFR3 ANTIBODY in Neuropathy

Thank you!