Thanks for replying! We have talked to the doctor on the phone, but the only advice at this point is: stop taking the new drug for now and go back to your former protocol. I did that last night. Still had the RLS, but maybe not as bad. Still kept me awake until about 4:30 AM. Ugh. I have an appointment on Monday. In the meantime….two more nights to go until then and now without the stronger antidepressant — back to citalaphram.