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Jul 1, 2017 · restless legs syndrome (RLS) and mirtazapine in Depression & Anxiety

Thanks for replying! We have talked to the doctor on the phone, but the only advice at this point is: stop taking the new drug for now and go back to your former protocol. I did that last night. Still had the RLS, but maybe not as bad. Still kept me awake until about 4:30 AM. Ugh. I have an appointment on Monday. In the meantime….two more nights to go until then and now without the stronger antidepressant — back to citalaphram.

Jun 30, 2017 · restless legs syndrome (RLS) and mirtazapine in Depression & Anxiety

Hi,
I recently started mirtazapine and have had a good initial reaction to the drug – my energy is better, my mood. The one rather major problem is it seems to trigger or exacerbate my RLS. I had been on tramadol (for back pain) about a week before starting mirtazapine and I have read that they can interfere with each other and cause RLS. My question is should I look for another antidepressant or is it possible that this will improve with time. Right now I am awake all night until about 5 AM when I catch a few hours of sleep. It is pretty rough.