Have you looked up the bad stuff Metropol does? I was on that one for a short while, but my heart rate kept dropping to the 40s, so moved on. Carvedilol was equally bad, but suppressed the migraines. Took 2 years of trying to get off carvedilol, but finally got off that one. Still have relatively low heart rate, but don't believe it is from the meds. I can recall when I was around 40 and went to give blood, I was a bicyclist then and rode daily, and was almost refused the donation due to the low heart rate. I'm almost 30 years past that almost refusal, stopped all beta blockers, take a few supplements, a statin, some Potassium, levothyroxine and losartan potassium. I'd have to say my Quad bypass was a great decision as it really did take care of most of my problems I had at the time of the surgery.