When I had my last appointment with the doctor, he took me off drugs because I had had 5 negatives in a row and it had been two years. At that appointment, I gave a sputum sample and lo and behold, it came back positive. I have not had a bronchoscopy. It appears that I intermittently test positive. My local doctor and Dr. Huitt at National Jewish will go by symptoms, CT scans, and colony count (magic number may be 50) in determining when and if (probably just when) I should return to the meds. Hoping and praying if it must be that it will be in future. Who knows! Have an appointment at National Jewish in November. Just wondering if there are others reading this blog who intermittently test positive after completing the drug treatment. Would like to hear from them.