I also have PVC's when I am having bloating/gas. I also have a hiatus hernia which makes me wonder if there is physical interference with the heart. Since I have rhythm issues, I am particularly sensitive to the PVC's. I have taken most of the PPI's at one time or another. They do work, but am currently on Zantac (pharmacist insists they have changed the formulation for RX) for a change. For certain, a trip to the chiropractor helps with the acid reflux, but I have also noticed that it helps with the PVC's "sometimes". The move is helps is between the shoulder blades. Could be coincidence, but I don't think so.