Weight gain with Prolia

Posted by laura1965 @laura1965, May 29, 2020

On April 9 I received the Prolia injection. Within six weeks I gained 4 pounds and several inches. I have always been very petite and thin, so this was a shock. Has anyone else experienced this with the injection?

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Yes, me too! Weight gain, Lethargy! I hate this treatment!


I have been on Prolia for almost three years. I am 5'2" and my weight remains basically the same (107 to 108 lbs.)


@migizii. I have been on Prolia for three years, also and actually lost 7 pounds this past year (not intending too)….I’ve not had any problems with this medication.

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