I had an ischemic stroke at 47 – I am now 52. No high cholesterol. The thought was a PFO – hole in my heart. I had it repaired. I still get headaches and things that seem like TIA’s – especially when stress is high. I saw a vascular neurologist who thinks it may be vascular related. Is this the type of thing that I could go to the Mayo Clinic for a 2nd opinion? I am noticing more of a rheumatoid arthritis type symptoms and I have read where it may even be connected. This has cost me my marriage of 25 years, and much self-esteem.