Stem Cell Treatment for Osteoporosis

Posted by psmnonna @psmnonna, Sep 19 8:44am

Here is info on using a person's own stem cells to treat osteoporosis. Looks very promising.
https://medicalxpress.com/news/2026-09-osteoporosis-fractures-fall-small-human.html
https://pubmed.ncbi.nlm.nih.gov/42727576/

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

One study with 10 patients makes me think much more research must be done. Stem cell therapy is a complicated process and is much more than just an infusion of your own cells. I have a friend that did it for Multiple Myeloma. It worked but it didn’t go smoothly. She did pre-treatment only to be delayed because something happened to her cells in the lab rendering them unusable. She had to start all over again!

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Profile picture for bswpb @bswpb

One study with 10 patients makes me think much more research must be done. Stem cell therapy is a complicated process and is much more than just an infusion of your own cells. I have a friend that did it for Multiple Myeloma. It worked but it didn’t go smoothly. She did pre-treatment only to be delayed because something happened to her cells in the lab rendering them unusable. She had to start all over again!

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@bswpb
Very true and I agree with you. Much larger studies over time will tell if this is actually a safe and viable alternative to the osteo meds. This is still promising to me, and I'm hoping for more research.

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Profile picture for psmnonna @psmnonna

@bswpb
Very true and I agree with you. Much larger studies over time will tell if this is actually a safe and viable alternative to the osteo meds. This is still promising to me, and I'm hoping for more research.

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@psmnonna it is promising but I don’t think it’s something I would consider for osteoporosis.

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Profile picture for bswpb @bswpb

One study with 10 patients makes me think much more research must be done. Stem cell therapy is a complicated process and is much more than just an infusion of your own cells. I have a friend that did it for Multiple Myeloma. It worked but it didn’t go smoothly. She did pre-treatment only to be delayed because something happened to her cells in the lab rendering them unusable. She had to start all over again!

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@bswpb , still, those results are very alluring!

"In the first two years after treatment, fractures caused by weakened bones fell by 94%, from eight fractures per year to 0.5 fractures per year, across the group. Post-treatment bone biopsies showed that the mean bone tissue area nearly doubled in just four months."

Wow! I know that ten subjects is very small, and likely skews toward healthy subjects due to self selection, but still pretty impressive. I read studies on lots of subjects, and often the increase/decrease in the average study is just barely beyond statistical insignificance. Can't wait to see this repeated on a larger scale.
It's good to have hope.

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Profile picture for boneoptimist @boneoptimist

@bswpb , still, those results are very alluring!

"In the first two years after treatment, fractures caused by weakened bones fell by 94%, from eight fractures per year to 0.5 fractures per year, across the group. Post-treatment bone biopsies showed that the mean bone tissue area nearly doubled in just four months."

Wow! I know that ten subjects is very small, and likely skews toward healthy subjects due to self selection, but still pretty impressive. I read studies on lots of subjects, and often the increase/decrease in the average study is just barely beyond statistical insignificance. Can't wait to see this repeated on a larger scale.
It's good to have hope.

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@boneoptimist yes it seems impressive but I would like to see a bigger study over a longer period of time and from more than one source! I have enough issues without putting myself through the pretreatment process for an unknown!

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Profile picture for bswpb @bswpb

@boneoptimist yes it seems impressive but I would like to see a bigger study over a longer period of time and from more than one source! I have enough issues without putting myself through the pretreatment process for an unknown!

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@bswpb , absolutely agree! I've never been a jump on the band wagon person!

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Thanks for letting us know about the study—even if it is small; it is promising. We at least can hope for the ones coming after us that they will have better options.

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Stem cell doesn't work for everyone or for every disorder. My friend underwent it for diffuse systemic scleroderma. For her it failed, and she lost the battle.

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