Saxenda and side effects of depression?

Posted by neilc @neilc, Jun 5, 2019

Hello, I am on Cipralex, mirtazipine and respirodone for depression and anxiety. My diagnosis is major depression with psychotic features. My weight loss Doctor says I am always hungry as a side effect of respirodone and cipralex. He mentioned a appetite suppressant called Saxenda. But I read up on it and one side effect of it ican be depression. I am weary of starting the drug because of this, Has anyone tried Saxenda who suffers from depression and anxiety? Did it worsen your depression?

Interested in more discussions like this? Go to the Depression & Anxiety group.

Hello @neilc,

While we wait for others to join in this discussion, I thought you might find it interesting to read a little about Sandexa from the website. Here is the link, just click on it and you will get some information. https://www.novocare.com/saxenda/savings-card.html?

Is your weight-loss doctor aware of your depression? Did your doctor have any other suggestions regarding your weight loss other than a med?

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@hopeful33250

Hello @neilc,

While we wait for others to join in this discussion, I thought you might find it interesting to read a little about Sandexa from the website. Here is the link, just click on it and you will get some information. https://www.novocare.com/saxenda/savings-card.html?

Is your weight-loss doctor aware of your depression? Did your doctor have any other suggestions regarding your weight loss other than a med?

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Thank you Teresa. Yes I am on a low carb high protein diet and have lost 14 lbs in in about three months which is ok but not great. I am seeing my weight loss Dr possibly next week again. In the three months I have had some set backs like the death of my Father and a 5 day fishing trip.

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@neilc

Thank you Teresa. Yes I am on a low carb high protein diet and have lost 14 lbs in in about three months which is ok but not great. I am seeing my weight loss Dr possibly next week again. In the three months I have had some set backs like the death of my Father and a 5 day fishing trip.

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That is good that you are making some progress toward more healthy eating. I am sorry to hear of the death of your father. The death of a parent can be quite a struggle, can't it? Perhaps you might be interested in participating in a discussion here on Connect about Loss and Grief. I opened up the discussion about the loss of my father and you might find that post to be helpful. Here is a link to that discussion, https://connect.mayoclinic.org/discussion/loss-and-grief-how-are-you-doing/?utm_campaign=search.

How long ago did your dad pass away, @neilc? Is your mother still living?

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Hi, @neilc – I also wanted to invite @katie215 and @johnbishop to this discussion for any input related to Liraglutide (Saxenda) and whether it might worsen your depression.

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Hi @neilc, I'm not familiar with Saxenda but if one of the side effects is depression which it appears to be, I would look for natural ways to suppress my appetite. I've used a couple of these tips, including drinking a full glass of water before a meal.

Ten natural ways to suppress appetite
https://www.medicalnewstoday.com/articles/320625.php

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@johnbishop

Hi @neilc, I'm not familiar with Saxenda but if one of the side effects is depression which it appears to be, I would look for natural ways to suppress my appetite. I've used a couple of these tips, including drinking a full glass of water before a meal.

Ten natural ways to suppress appetite
https://www.medicalnewstoday.com/articles/320625.php

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Good article, @johnbishop and another great excuse for eating dark chocolate, which I love. I buy the large high-quality candy bars and recently have had a couple of dark chocolate with ginger ones. So that knocks off two of the suggestions at once! I buy the bars and then break them into the predefined squares and eat a couple, generally after breakfast, but maybe I should switch that to before dinner.
JK

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@contentandwell

Good article, @johnbishop and another great excuse for eating dark chocolate, which I love. I buy the large high-quality candy bars and recently have had a couple of dark chocolate with ginger ones. So that knocks off two of the suggestions at once! I buy the bars and then break them into the predefined squares and eat a couple, generally after breakfast, but maybe I should switch that to before dinner.
JK

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John, I, too, joined the chocolate snack since I read that it is a good antioxidant and I know that flavor is important to a diet. I eat two squares after dinner, usually, but sometimes after lunch if I only have a salad. The ones I eat have only ninety calories, low sugar, and have orange bits in them. After dinner I wash the chocolate down with a glass of milk in preparation for the sleepiness that seems to come from the milk. Then I can get to sleep easily, or I can drink camamille tea which does the job of bringing on sleepiness. Tonight is an exception because I have too much on my mind to process, and I have been awake all night. Depression is not a problem for me because I indulge in a prayer life which erases my loneliness from living alone. I recently walked away from problems which were not being addressed and now need to get it out of my head. Life is good when you engage with and help others. I seldom use food for comfort anymore, and I have lost 6 pounds from not being able to cook with a fractured shoulder injury. I'm getting better now. Dorisena

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@dorisena

John, I, too, joined the chocolate snack since I read that it is a good antioxidant and I know that flavor is important to a diet. I eat two squares after dinner, usually, but sometimes after lunch if I only have a salad. The ones I eat have only ninety calories, low sugar, and have orange bits in them. After dinner I wash the chocolate down with a glass of milk in preparation for the sleepiness that seems to come from the milk. Then I can get to sleep easily, or I can drink camamille tea which does the job of bringing on sleepiness. Tonight is an exception because I have too much on my mind to process, and I have been awake all night. Depression is not a problem for me because I indulge in a prayer life which erases my loneliness from living alone. I recently walked away from problems which were not being addressed and now need to get it out of my head. Life is good when you engage with and help others. I seldom use food for comfort anymore, and I have lost 6 pounds from not being able to cook with a fractured shoulder injury. I'm getting better now. Dorisena

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@dorisena I really think chocolate has an anti-depressant effect. I will always have a picture in my mind of my daughter, when she was still in a highchair, eating M&Ms. The look on her face was positively euphoric and dreamy!
JK

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Yes, when I am tired and planning to play a concert with my community band group, I eat a little chocolate before the concert and the small caffeine in the chocolate seems to give me just enough of a boost to really enjoy playing and doing well with the group. At my age, daily mental and physical boosts are a requirement. We had one granddaughter who loved cheddar cheese as a toddler and actually preferred it to cookies, which surprised the kitchen ladies at her summer Bible School events. So we didn't push the sweets and now as a grown woman she is a careful eater, and even stays too thin, in my opinion, however that is her choice. I wish I could get my endocrinologist to boost my thyroid medicine because I fought low thyroid and finally had it removed due to cancerous nodes. Now she keeps the numbers low because she says it wards off more cancer, but I am tired most of the time. I refuse to be depressed because I have a very good life here on the beautiful farm. We all need people in our lives to love and to be loved. Dorisena

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In reply to @amydean "a" + (show)
@amydean

Hi Amy, welcome back to Mayo Clinic Connect. Your message only says "a". Will you post again?

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I was on Saxenda for 4 weeks on by the 4th week I was so depressed I couldn’t stand it. I’ve been off it for 3 days and already feel 5 times better. That is my experience for what is worth. It did work as a weight loss drug though and I had no real cravings or appetite.

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