Hi @john0416, welcome to Connect. I couldn't find much scholarly information about Renadyl (formerly known as Kibow biotics), a probiotic supplement, only the company's website and claims. This small study of 25 patients done in 2016 looks promising http://www.iraj.in/journal/journal_file/journal_pdf/6-235-1458645583104-111.pdf

I'm tagging @nycdave7 @rans @kamama94 @sissieann @marvinjsturing and @trishanna to see if they may have any information on the efficacy of Renadyl.

John, do you have kidney disease? Has Renadyl been recommended by your physician?

@john0416 According to NIH, there's some evidence Renadyl does help. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132402/

I have no experience with Renadyl.

I haven't been put on any meds yet. See a Neph. the 15 th of Feb. for the first time.

I have rapidly changing numbers and have gone from normal range to stage 3 in a flash .

Five years ago I had bladder cancer and had my bladder removed and had the pouch made out of intestine section modification done . This led to frequent UTI infections which have been minimized by taking two antibiotics daily.

I now realize that taking the antibiotics kills the good biotics in the digestive track that feed off of creatinine in the blood .
That increases the creatinine level in the blood which increases the workload on the kidneys .
I have stopped taking all antibiotics and started taking probiotic Renadyl
in an attempt to stop and hopefully improve the creatinine levels in my blood .

I realize this puts me at risk for UTI but priority # 1 right now is kidneys .

There is another possible cause that involves a slow draining kidney due to a partially blocked ureter where it connects to the pouch ((scar tissue )) ,

If my stopping antibiotics and taking Renadyl does not show any positive effects on Feb , 6 blood test ,,, I will likely have a drain tube coming out of my back , draining the slow draining kidney into an exterior bag .
Meanwhile I would still be draining the other kiney with a catheter through my stoma .
If that helps then an attempt will be made to put a stint in the partially blocked ureter .

I sure am hoping one of these actions fixes the situation . I am already an incomplete quadriplegic ,,,,(( due to a twenty foot fall at work and a crushed cervical spine fused from C2 to T1 along with 3 metal rods and 14 screws ))

who has to drain his urine with a catheter through a stoma in his gut . Adding kidney failure to the mix , well , it is getting to be a bit much .

The doctors have not recommended the Renadyl .
All the kidney doctor recommended in December was stopping one of the antibiotics .
The other steps I took on my own and made them aware .
Urology is wanting to do the drain test ASAP but I have quality of life concerns
considering what I already am going through . I want to see step one results first .

@john0416 Am going to ask my neph about Renadyl next week, especially since I recently was on a round of antibiotics. Hope you see positive effects with your next lab. One step at a time is a good motto for all of us, I think. Wishing you well..

I have Diverticulosis and have been hospitalized twice under heavy antibiotics so I'm really interested in Renaldyl. I'm not sure if my kidney problems could be related to the antibiotics or not. "D_____ if you do d_____ if .don't"

it is my impression that long term use is the real problem … but I am by no means a medical professional in any way . It does sound like having good biotics in the digestive tract is a plus for the kidneys ,

I agree – as little as it takes to get the job done.( antibiotics )

my labs taken on 2/6 show ***BIG*** improvement .
My creatinine and GFR numbers moved the right way .
Creatinine moved 67% of the distance from where it was on 1/4 back to normal ….
and GFR moved 41% of the distance back to normal .

I have taken several steps besides taking Renadyl but I believe the Renadyl definitely has been a factor .
If I have continued improvement on my next test on 3/6 that will pretty much seal the deal
as the Renadyl says it takes three months for full effect
and I have not even been on for a whole month yet .