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PSA Nadir main deciding factor when one can start on Intermittent ADT?

Posted by ava11 @ava11, Mar 1, 2025

I have been on orgovyx from April 1st,2024(11months). I had SBRT 5 sessions started on April 8th and finished on April 18th.
My PSA on October 7, 2024 was 0.06
PSA on Feb 27,2025 is 0.03 (50% reduction in about 4 months)

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wwsmith | @wwsmith | Jan 11 9:26pm
In reply to @pfj0650 "@jeffmarc If Gleason 7 unfavorable (4+3) and only got 20 fractions of 3 Gy’s each and..." + (show)
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@jeffmarc
If Gleason 7 unfavorable (4+3) and only got 20 fractions of 3 Gy’s each and decipher .88 How long should I stay on orgovyx.? Lymph nodes not radiated. No boost to tumor. Radiation started on day 11 of orgovyx no testosterone was 750 before radiation psa had gone from 9.4 to 11.9 diagnosed prostate cancer July 20. Radiation started Nov 10. Psa today .209 and testosterone < 2.5. I am I month post radiation and 2 mo post onset of orgovyx. I wanted boost to MR detectable tumor doctor refused also wanted whole pelvis radiated doctor denied. Now recommending only 6 month of adt. I think I need it longer as
Decipher.88 and radiation treatment borderline?

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@pfj0650 I was 3+4 with Decipher 0.81. My RO at Houston MD Anderson recommended 1 year of ADT for me. Your situation is worse than mine so 1 year of ADT seems appropriate. See my bio for more details.

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