Pros and Cons of Prolia

Posted by alicia49 @alicia49, Aug 21 4:01pm

Hi my name is Alicia. I have been receiving treatment for four years since being diagnosed. For 12 months I was on Evenity with no issues. My doctor transitioned me to ReClast, which is an annual infusion, which I took for 3 years with no issues. After taking Evenity my Dexa scan showed great improvement. After my last ReClast infusion, which was July 2026 I had another scan and was shocked when it showed deterioration of my Evenity results. My doctor wants to put me on Prolia after a 12 month holiday, which is required. I have read a lot about Prolia and I don’t like what I have been reading. I talked to my doctor about it but she was not forthcoming with alternatives. I wanted to see if there was some treatment that would regrow the bone I had lost. Is there something out there that will do that and then I will feel more comfortable about moving towards something like Prolia. Thanks for your help.

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There is a lot of stuff out there but no way to know if they are going to work! Natural stuff really needs excellent diet and exercise including resistance bands or weights. Bisphosphonates don’t do the greatest job as far as I can tell. I didn’t want to take Prolia but also don’t want any more fractures so I went with it. I will have my 3rd injection next month. It really hasn’t been so bad!

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Alicia, you might try Forteo or Tymlos. I'm partial to Forteo because it's the medication I take and have had no side effects with. These two drugs remove weak bone before adding new bone. They build the strongest, most fracture resistant bone.
Prolia works for many. It is difficult to stop. You really have to take yet another year of Reclast if you do otherwise you are likely to fracture. You might plan to stay on Prolia, but several risks might give you reason to stop. Because Prolia builds on top of damaged bone and because the bone with adds is less vascular and brittle there is the risk of osteonecrosis and atypical femur fracture.
Some experience unbearable side effects with Prolia.
I'd take Prolia if there were no other choices.
Bless your choice.

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Profile picture for bswpb @bswpb

There is a lot of stuff out there but no way to know if they are going to work! Natural stuff really needs excellent diet and exercise including resistance bands or weights. Bisphosphonates don’t do the greatest job as far as I can tell. I didn’t want to take Prolia but also don’t want any more fractures so I went with it. I will have my 3rd injection next month. It really hasn’t been so bad!

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@bswpb thank you. I appreciate your feedback.

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Profile picture for gently @gently

Alicia, you might try Forteo or Tymlos. I'm partial to Forteo because it's the medication I take and have had no side effects with. These two drugs remove weak bone before adding new bone. They build the strongest, most fracture resistant bone.
Prolia works for many. It is difficult to stop. You really have to take yet another year of Reclast if you do otherwise you are likely to fracture. You might plan to stay on Prolia, but several risks might give you reason to stop. Because Prolia builds on top of damaged bone and because the bone with adds is less vascular and brittle there is the risk of osteonecrosis and atypical femur fracture.
Some experience unbearable side effects with Prolia.
I'd take Prolia if there were no other choices.
Bless your choice.

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@gently thank you for your feedback it very helpful.

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Profile picture for bswpb @bswpb

There is a lot of stuff out there but no way to know if they are going to work! Natural stuff really needs excellent diet and exercise including resistance bands or weights. Bisphosphonates don’t do the greatest job as far as I can tell. I didn’t want to take Prolia but also don’t want any more fractures so I went with it. I will have my 3rd injection next month. It really hasn’t been so bad!

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@bswpb thank you for your feedback.

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@alicia49 My wife has been getting Prolia shots for about two years without incident. The downside is that, even with Medicare, it costs $300/shot, twice a year.

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heisenberg34, has your wife had any side effects with Prolia?

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Profile picture for heisenberg34 @heisenberg34

@alicia49 My wife has been getting Prolia shots for about two years without incident. The downside is that, even with Medicare, it costs $300/shot, twice a year.

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@heisenberg34 thank you for your feedback. Yes, all these drugs have a heavy out of pocket. I was wondering if her Dexa scans reflect a positive impact on her bones since taking Prolia?

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I’m 76 and have been on Prolia for 8 years. I haven’t experienced any bad side effects and my scores have been staying steady. I assume I’ll be on Prolia forever. I’m lucky as my insurance covers the cost.I did have arm pain for about 2 weeks once, but now always ask to have my shot injected slowly, as I read that that will help with any arm, muscle pain from the shot. And it worked.

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Profile picture for alicia49 @alicia49

@heisenberg34 thank you for your feedback. Yes, all these drugs have a heavy out of pocket. I was wondering if her Dexa scans reflect a positive impact on her bones since taking Prolia?

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@alicia49 I've been on Prolia for 4 years without any negative side effects, and my Dexa scores have been positive.

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