My nephew in Colorado needs a kidney transplant due to Alport Syndrome. He has a living donor ready to go. It’s being held up because his red blood cell count is low. He’s been told that a blood transfusion would reduce the odds of a successful transplant to 50-50, even if the transfusion comes from the donor. He’s chosen to get treated for the low count with an injection to boost it. He’ll only do a transfusion as a last resort.
In layman terms, can you help me understand why a blood transfusion causes an increased risk of rejection in a kidney transplant.