Possible PMR OR Lora diagnosis

Posted by marilyncarkner @marilyncarkner, Feb 20, 2019

I am a very active 71 year old who works out regularly. I started with creeping stiffness in December . My GP has referred me to a Rheumatologist but while waiting she started me on 50 mgs 1 st week 45 mgs 2 nd week and so on till I am down as I can be with it symptoms.Not sure if it is PMR or Lora The first 2 weeks were magic and then whenI I hit 40 mgs the symptoms reappeared ( damn) and on such a high dose …. frustrated Maybe Methyltrexate is the answer….any thoughts.

Interested in more discussions like this? Go to the Polymyalgia Rheumatica (PMR) group.

You are at the average age for PMR to start. I have had PMR for 14 years. I presume the med you are referring to is prednisone. As the dose is reduced symptoms often reappear. Given a few days they will often disappear. PMR is condition that often seems to change from one day to the next. I was in a study about 10 years or so back. Whatever was in the weekly shots I was taking left me feeling wonderful. However, the shots had one bad side affect and the study was stopped. I don't like the side affects of prednisone, but I have pretty much learned to live with them.


Hello @marilyncarkner, Welcome to Mayo Clinic Connect. I have had 2 occurrences of PMR. The first lasting about 3 years and the second about a year and half. Both occurrences were treated starting with 20 mg of prednisone and tapering slowly off. Sometimes tapering too fast brings the pain back quickly. There are a couple of discussions here on Connect that you and @edithmiller might want to join in and see what others are sharing about their PMR journey.

– Polymyalgia rheumatica https://connect.mayoclinic.org/discussion/poly-myalgia-rheumatica/
– Diagnosed with PMR 2 1/2 years ago. How do I manage the extreme pain? https://connect.mayoclinic.org/discussion/i-was-diagnosed-with-pmr-2-12-years-ago-steroids-didnt-help/
– PMR and Methotrexate https://connect.mayoclinic.org/discussion/pmr-and-methotrexate/

Has your doctor mentioned trying methotrexate?

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