Parkinson's disease will be curable with cortisol

Posted by robjohn @robjohn, Sun, May 26 9:55pm

I just ran across this article while researching a blood test that showed my cortisol is very low. PUBLIC RELEASE: 25-APR-2017
Parkinson's disease will be curable with cortisol
DGIST (DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY)

Does anyone know more about this?

@robjohn, is this article?
https://www.eurekalert.org/pub_releases/2017-04/dgi-pdw042517.php
It was also written about in Parkinson's News Today in 2017 https://parkinsonsnewstoday.com/2017/05/09/study-reports-stress-hormone-could-be-used-to-treat-parkinsons-disease/

I found a follow-up study (2019) “Endurance Exercise Reduces Cortisol in Parkinson’s Disease With Mild Cognitive Impairment,” https://parkinsonsnewstoday.com/2019/05/24/endurance-exercise-helps-manage-cortisol-levels-parkinsons-patients/

"Physical exercise is associated with a lower production of cortisol in healthy individuals, and there is evidence that it may also reduce the risk and rate of Parkinson’s progression."
"While other studies are needed to confirm if lowering cortisol with physical exercise works for delaying disease worsening, this data supports the further exploration of the role played by the hormone in non-motor symptoms of Parkinson’s."

It would seem that exercise is important as many members have written about here on Connect. What keeps you active, RobJohn?

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I OWE I OWE SO ITS OF TO WORK I GO. Seriously I take care of our home and 20 acres, raise a few sheep. Also, do some custom mowing and do some tractor repair. I keep wondering how I managed all this while driving a truck 150,000 miles per year. I never learned how to be a loafer. I will read your links, I have been looking at this disease from many angles and don't intend to go down easy. My cortisol May 4 was 2.0 at 08:00.

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@colleenyoung

@robjohn, is this article?
https://www.eurekalert.org/pub_releases/2017-04/dgi-pdw042517.php
It was also written about in Parkinson's News Today in 2017 https://parkinsonsnewstoday.com/2017/05/09/study-reports-stress-hormone-could-be-used-to-treat-parkinsons-disease/

I found a follow-up study (2019) “Endurance Exercise Reduces Cortisol in Parkinson’s Disease With Mild Cognitive Impairment,” https://parkinsonsnewstoday.com/2019/05/24/endurance-exercise-helps-manage-cortisol-levels-parkinsons-patients/

"Physical exercise is associated with a lower production of cortisol in healthy individuals, and there is evidence that it may also reduce the risk and rate of Parkinson’s progression."
"While other studies are needed to confirm if lowering cortisol with physical exercise works for delaying disease worsening, this data supports the further exploration of the role played by the hormone in non-motor symptoms of Parkinson’s."

It would seem that exercise is important as many members have written about here on Connect. What keeps you active, RobJohn?

Jump to this post

@colleenyoung Great articles, Colleen. Yes, all of us with a PD diagnosis have found that we feel and move better with exercise.

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@colleenyoung

@robjohn, is this article?
https://www.eurekalert.org/pub_releases/2017-04/dgi-pdw042517.php
It was also written about in Parkinson's News Today in 2017 https://parkinsonsnewstoday.com/2017/05/09/study-reports-stress-hormone-could-be-used-to-treat-parkinsons-disease/

I found a follow-up study (2019) “Endurance Exercise Reduces Cortisol in Parkinson’s Disease With Mild Cognitive Impairment,” https://parkinsonsnewstoday.com/2019/05/24/endurance-exercise-helps-manage-cortisol-levels-parkinsons-patients/

"Physical exercise is associated with a lower production of cortisol in healthy individuals, and there is evidence that it may also reduce the risk and rate of Parkinson’s progression."
"While other studies are needed to confirm if lowering cortisol with physical exercise works for delaying disease worsening, this data supports the further exploration of the role played by the hormone in non-motor symptoms of Parkinson’s."

It would seem that exercise is important as many members have written about here on Connect. What keeps you active, RobJohn?

Jump to this post

I have had a Parkinson's diagnoses for several years. I am 70 and take 1 mg Rasagiline (Azilect) daily and I exercise every day. As a result the Parkinson's has not noticeably progressed. I can literally tell the difference if I have to go a couple days without exercise.
What my immediate concern is dealing with Parkinson's and recurring prostate cancer. I would like to get feedback from anyone else who is dealing with both issues and what their personal experience is.

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@safari1949

I have had a Parkinson's diagnoses for several years. I am 70 and take 1 mg Rasagiline (Azilect) daily and I exercise every day. As a result the Parkinson's has not noticeably progressed. I can literally tell the difference if I have to go a couple days without exercise.
What my immediate concern is dealing with Parkinson's and recurring prostate cancer. I would like to get feedback from anyone else who is dealing with both issues and what their personal experience is.

Jump to this post

Sorry, I had my prostatectomy in 2000 and my Parkinson’s wasn’t diagnosed until 2014 though, in looking back, there were a number of obvious symptoms many years prior so I don’t see that can help you any.

But maybe I can learn from you. I’ve never heard of anyone on Azilect alone -no Sinemet. What were your symptoms?

Now I have a tumor on my adrenal gland messing with my cortisol and I’m producing too little. I’m wondering if/how that is related to the rest of this.

Steve

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Hello @safari1949 and @ggopher

Here is some information from WebMD regarding Azilect. It is a med that can be used alone (especially in the early stages of PD) or together with other meds like Sinemet.
https://www.webmd.com/drugs/2/drug-144443/azilect-oral/details
@safari1949 I'm so glad to hear that you are doing so well with the med and regular exercise. I agree with you that if I don't exercise for a few days, my PD symptoms do get worse. Is there any type of exercise that is most beneficial for you?

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@hopeful33250

Hello @safari1949 and @ggopher

Here is some information from WebMD regarding Azilect. It is a med that can be used alone (especially in the early stages of PD) or together with other meds like Sinemet.
https://www.webmd.com/drugs/2/drug-144443/azilect-oral/details
@safari1949 I'm so glad to hear that you are doing so well with the med and regular exercise. I agree with you that if I don't exercise for a few days, my PD symptoms do get worse. Is there any type of exercise that is most beneficial for you?

Jump to this post

Learn something every day- thanks

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@hopeful33250

Hello @safari1949 and @ggopher

Here is some information from WebMD regarding Azilect. It is a med that can be used alone (especially in the early stages of PD) or together with other meds like Sinemet.
https://www.webmd.com/drugs/2/drug-144443/azilect-oral/details
@safari1949 I'm so glad to hear that you are doing so well with the med and regular exercise. I agree with you that if I don't exercise for a few days, my PD symptoms do get worse. Is there any type of exercise that is most beneficial for you?

Jump to this post

I do some basic yoga that keeps me flexible and some light weights. I really believe the bicycle riding is probably the best although I get great workouts on the elliptical. I always feel better after I finish Especially when it’s hard to get started.

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@ggopher

Sorry, I had my prostatectomy in 2000 and my Parkinson’s wasn’t diagnosed until 2014 though, in looking back, there were a number of obvious symptoms many years prior so I don’t see that can help you any.

But maybe I can learn from you. I’ve never heard of anyone on Azilect alone -no Sinemet. What were your symptoms?

Now I have a tumor on my adrenal gland messing with my cortisol and I’m producing too little. I’m wondering if/how that is related to the rest of this.

Steve

Jump to this post

Basically a tremor in my right side I missed some weakness on the right side as well. Of course my hand writing has been affected along with my voice at times. From what I read the tumor in your adrenal gland could have been partially responsible for your Parkinson’s. But I am not a doctor

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Missed should’ve been have

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@robjohn

I OWE I OWE SO ITS OF TO WORK I GO. Seriously I take care of our home and 20 acres, raise a few sheep. Also, do some custom mowing and do some tractor repair. I keep wondering how I managed all this while driving a truck 150,000 miles per year. I never learned how to be a loafer. I will read your links, I have been looking at this disease from many angles and don't intend to go down easy. My cortisol May 4 was 2.0 at 08:00.

Jump to this post

I am the same way and I plan on fighting for life and a quality life for myself and my family

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