I have been battling MCTD for 12 + yrs. I am currently in a flare with severely painful hands... (swollen, red), fatigue and overall joint pain, low grade fever. I am on Plaquenil. I also have persistent skin rashes on my hands,arms and legs and alopecia. Have been on many different meds and am under the care of a rheumatologist. Have been to several dermatologist but all they offer is creams that do not work. I hate the bouts of fatigue!!! I am new to this site but am excited to talk with other MCTD patients!!