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Stem Cells and Growth Factors for Osteoarthritis: Hope or Hype

Wed. Mar 23, 2016 at 12:00 pm CDT

Mayo Clinic hosted an interactive webinar on Stem Cells and Growth Factors on Wednesday, March 23, 2016. Medical Director for Sports Medicine – Minneapolis, and Team Physician for the Minnesota Timberwolves & Lynx, Jonathan Finnoff, D.O., and Physical Medicine & Rehabilitation expert physician, Jacob Sellon, M.D., discussed the hope and hype around a newly emerging, exciting, and game changing area of medicine that harnesses the body’s natural healing abilities. A live question and answer session followed the presentation. You can watch a recording of the webinar now. View transcript.

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williabdw

williabdw wrote:

I am a 70 yr old and have had one knee replacement. The other one is bone on bone. What are my chances that this treatment would be successful. Also would it hinder my getting a knee replacement if it [...] View full text  

Posted Wed, Jan 11 at 7:47pm CDT

Hello @williadbw, welcome to Connect.

This webinar took place in the past, however, I suggest you pose your question to other members in the following discussion, http://mayocl.in/2iosIsG. It is an active discussion taking place between members about stem cells vs. knee replacements.

In that discussion, you will meet other members asking the same kinds of questions who will be able to share their experiences with you.

Posted Thu, Jan 12 at 8:59am CDT

jrohrmayer

jrohrmayer wrote:

Hello, I just watched your webinar, I am a 52 year old man that feel out of a tree in 2001, shatter my left ankle and heel, I have been through 3 different fusion surgery since my accident, with these, [...] View full text  

Posted Wed, Jan 4 at 3:51pm CDT

Hello @jrohrmayer, welcome to Connect. Thank you for your reply to this webinar.

This webinar unfortunately took place in the past, however, I suggest you pose your question to other members in the following discussion, http://mayocl.in/2iosIsG. It is an active discussion taking place between members about stem cells vs. knee replacements. While it does not directly apply to ankles, it is a relevant discussion about stem cell treatments.

Connect is a place for members to share experiences, advice, and comforting words with one another. This would be a great question to ask a physician, if you are looking for a second opinion from mayo clinic, use this link, http://mayocl.in/1mtmR63.

I also have had an ankle fusion, along with end-stage arthritis in my right ankle and a right knee replacement. It has been frustrating trying to adapt my high level physical activity with my new reality of having to dial back. I have just learned to adapt and have recently been playing Sled Hockey (look it up, it is pretty awesome and worth trying if you have lower body injuries).

I hope this helps. Feel free to ask me any questions on how to use Connect.

Posted Wed, Jan 4 at 6:51pm CDT

rkiper

rkiper wrote:

Hello, and thank you for putting together the webinar. I am interested in seeing if the treatments may be an option for me. I am (or was) a highly active 45 year old male that injured the meniscus in my [...] View full text  

Posted Wed, Apr 20 at 7:49am CDT

jerads

jerads wrote:

Hopefully Dr Finnoff or Dr Sellon can answer this. I have two lumbar disc herniations and am looking for anything that could help. I am a 35 yr old male in good health (except for the spine). There are several [...] View full text  

Posted Mon, Apr 4 at 9:49am CDT

jbartelt

Jennifer Bartelt replied:

Hi, jerads. Dr. Wenchun Qu, in the Mayo Clinic Department of Physical Medicine and Rehabilitation, is currently studying the effects of stem cells on spinal discs and is using bone marrow concentrate for some spine conditions. We recommend visiting: http://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-services/regenerative-medicine-consult-service for a consultation. We wish you the very best.

Posted Tue, Apr 5 at 5:10pm CDT

joancoles

joancoles wrote:

I wrote in a question as the seminar was on and have not seen a reply. Could I have missed it? Thank you

Posted Mon, Apr 4 at 9:48am CDT

jbartelt

Jennifer Bartelt replied:

Hi, joancoles. We are working to post these in the next two days. You should see your response soon! You'll receive an email when it is posted. Thanks!

Posted Mon, Apr 4 at 2:53pm CDT

Anonymous wrote:

Where do I find the answer to my questions of April 2?

Posted Sun, Apr 3 at 3:44pm CDT

jbartelt

Jennifer Bartelt replied:

Your answer should appear very soon. Thanks!

Posted Mon, Apr 4 at 2:53pm CDT

Want to continue to connect with other patients on this topic? Join the discussions in Bones, Joints & Muscles Group https://connect.mayoclinic.org/group/arthritis-and-joint-conditions-268850/?tab=discussions. Ask questions, get answers and connect.

Posted Sat, Apr 2 at 11:37am CDT

Anonymous wrote:

I'm 70 with osteoarthritis in the hip. Would AmnioFix cell injection be helpful? Does cartilage completely wear away (anything to inject into)? Supplements were mentioned, can you suggest any that would be helpful? Thank you.

Posted Fri, Apr 1 at 4:50pm CDT

jbartelt

Jennifer Bartelt replied:

Technically, AmnioFix does not have any stem cells. AmnioFix is a created by processing placental tissue. We are not aware of any evidence that AmnioFix is effective for hip osteoarthritis. Regarding dietary supplements, there is little evidence that any particular supplement provides significant benefit for hip osteoarthritis. The difficulty with nutritional supplements is that they are not FDA regulated, so frequently the tablets do not contain the ingredients listed on the bottle.

Posted Tue, Apr 5 at 5:06pm CDT

pale

pale wrote:

If it's proven, how come no one can provide a specific citation showing any likihood of favorable results from HA injection in the hip for humans? Is there any reference to a study concerning hip osteoarthritis that indicates Hyaloronic acid [...] View full text  

Posted Wed, Mar 30 at 9:36pm CDT

jbartelt

Jennifer Bartelt replied:

Studies regarding hyaluronic acid and efficacy for hip osteoarthritis have been mixed. A recent trial showed there was some short term benefit for a few months, whereas PRP provided better relief and lasted at least 12 months (duration of the study).

http://www.ncbi.nlm.nih.gov/pubmed/26797697

Another recent review article discusses the research related to viscosupplementation and osteoarthritis:

i. Semin Arthritis Rheum. 2015 Oct;45(2):140-9. doi: 10.1016/j.semarthrit.2015.04.011. Epub 2015 Apr 30.
Consensus statement on viscosupplementation with hyaluronic acid for the management of osteoarthritis.
Henrotin Y1, Raman R2, Richette P3, Bard H4, Jerosch J5, Conrozier T6, Chevalier X7, Migliore A8

Posted Tue, Apr 5 at 5:02pm CDT

jbartelt

Jennifer Bartelt replied:

The second link didn't work. Try this: http://www.ncbi.nlm.nih.gov/pubmed/26094903

Posted Tue, Apr 5 at 5:04pm CDT

bnelson56401

bnelson56401 wrote:

i have osteoarthritis in both knees they are bone on bone. i am in real pain to walk or stand. I have had many different kinds of injections in which i only get 6 to 8 weeks relief. i am [...] View full text  

Posted Tue, Mar 29 at 3:18pm CDT

jbartelt

Jennifer Bartelt replied:

These treatments are typically considered experimental by insurance companies and are usually not covered by insurance. We recommend checking with your insurance company regarding coverage for specific conditions.

Posted Tue, Apr 5 at 2:51pm CDT

constancebay

constancebay wrote:

Pale, I can't cite any studies but I do have personal experience with hyaloronic acid injection. I have moderate arthritus in both hips, left being more problematic. Being in considerable pain I was given an imagery guided cortisone shot in [...] View full text  

Posted Tue, Mar 29 at 10:09am CDT

pale

pale replied:

Thanks for your personal input. I noticed on the seminar they said no

weight bearing and to use crutches for a week after injection I guess so to

help let the HA set and not dissipate into the body as fast. I understand

there's a greater chance of infection using cortizone within six months of

surgery and it damages the cartilage if you're trying to preserve what

remains so I've decided not to even try steroids.



I bought a second hand audi 4 sedan that is very comfortable to drive

(getting in and out's still difficult) but I agree most cars cause spasms

and pain. I have also been doing yoga and statonary cycling with (light)

weight training since it's difficult to walk and I don't wish to lose any

more range of motion or muscle tone. Everyone tells me to get my hip

replaced but I want to try the HA injection first only there's doesn't seem

to be any study supporting having this done to the hip that I can find.



Has anyone at least located the studies mentioned in the video conference?

Is there a monitor to this seminar discussion that can give feedback or

cite the specific references used? I need to find some official paper

supporting this (HA/PRP injection) procedure for the hip and am hoping

someone in this forum might know of any actual studies concerning these

injections (other than steroids) done in the hip.

Posted Tue, Mar 29 at 2:06pm CDT

pale

pale wrote:

Can anyone please cite a study where prp/HA injection into the hip has any promise? It seemed studies were refered to in the stem cell for osteoarthritis seminar but I have been unsucessful in locating any specific study supporting hyaloronic [...] View full text  

Posted Tue, Mar 29 at 9:09am CDT

alyson

alyson wrote:

I have pretty bad muscle degeneration problem on my legs and most of muscles surrounding my knee joints are gone. My doctor told me that normal people walk with muscles, but I walk with tendons and bones. Because of that [...] View full text  

Posted Sun, Mar 27 at 2:07am CDT

kelseydm

Kelsey Mohring replied:

Hi @alyson. Welcome to Connect! I'm so sorry to hear what you are going through... that sounds painful. Does anything seem to help improve the pain or inflammation?

I've moved your inquiry over to a thread entitled, "Stem Cells and Growth Factors for Osteoarthritis: Hope or Hype" where members like @torycat, @nadamarie, @janekircher and @joancoles are discussing a recent webinar Mayo Clinic held on stem cells and regenerative medicine. You can also watch a video of the webinar which you might find interesting.

In terms of the cost and insurance coverage, you can call the billing and insurance department at 800-660-4582 and they should be able to answer that. Hope this helps!

Posted Sun, Mar 27 at 9:01pm CDT

jbartelt

Jennifer Bartelt replied:

Thank you for joining us for our webinar. With each individual’s case being very different, we cannot offer direct medical advice over the Connect platform. If you would like to seek consultation at Mayo Clinic, call 612-313-0520 for our Minneapolis location or 507-266-9100 for our Rochester location. You can also visit http://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-services/regenerative-medicine-consult-service for more information about our services. We wish you the very best.

Posted Mon, Apr 4 at 9:03am CDT

suebreen54

suebreen54 wrote:

Hi sue breen i live in Adirondack mountains and i can't get the webinar. Can i read it? I have a question about stem cell in the future do you see it possibly regerating degenerated dics as in degenerated dics?

Posted Sat, Mar 26 at 11:23am CDT

Hi @suebreen54, the transcript of the webinar has been posted to Connect. Now you can read the presentation. You'll find it here: https://connect.mayoclinic.org/discussion/stem-cells-and-growth-factors-for-osteoarthritis-hope-or-hype-26c156/

Posted Sat, Apr 2 at 7:41pm CDT

jbartelt

Jennifer Bartelt replied:

Yes. Currently Mayo Clinic is studying the ability of stem cells to treat spine conditions. We recommend visiting the Mayo Clinic Center for Regenerative Medicine website to learn more: http://pmrblog.mayoclinic.org/discussion/mayo-clinic-pmr-to-assist-clinical-trial-for-stem-cell-treatment-for-disc-degeneration/.

Posted Mon, Apr 4 at 9:06am CDT

wendy43

wendy43 wrote:

When you answer these posted questions will your answers be posted so all can see? Many of these questions are the same ones many of us want to ask.

Posted Fri, Mar 25 at 11:47am CDT

jbartelt

Jennifer Bartelt replied:

Yes, we are working diligently to get all questions answered. Thanks!

Posted Mon, Mar 28 at 10:41am CDT

joancoles

joancoles wrote:

I would love to hear how you make out. We moved from Johns Creek last Aug. and now divide our time between Az and Co. I need to determine the best place to seek treatment.

Posted Fri, Mar 25 at 9:18am CDT

jbartelt

Jennifer Bartelt replied:

Currently, bone marrow concentrate (stem cell) injections are offered at the Rochester, Minneapolis, and Florida campuses. There are plans to offer this treatment in Arizona later this year. Platelet-rich plasma injections are currently offered at all four sites. Learn more here: http://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-services/regenerative-medicine-consult-service.

Posted Mon, Apr 4 at 9:10am CDT

candbtrav

candbtrav wrote:

Is there any research on using this with finger joints, I am a professional pianist and just developed this in the last two years, but now it is in every finger on both my hands. I am in pain all [...] View full text  

Posted Fri, Mar 25 at 8:45am CDT

jbartelt

Jennifer Bartelt replied:

We offer treatment in the finger joints. For more information, visit mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-services/regenerative-medicine-consult-service

Posted Mon, Apr 4 at 9:11am CDT

joancoles

joancoles wrote:

We just moved from Atlanta and I used Emory many times when there and may consider investigating them for stem cell. I would love to hear how u make out. Joan

Posted Fri, Mar 25 at 5:18am CDT

Hi @Joancoles, we removed your phone number from your message as the chat stream is public. If you would like to share personal contact information with another Connect member, I recommend using the Private Message function. Simply click a member's username and then click the envelope icon in their profile.

Posted Fri, Mar 25 at 7:08am CDT

Posted two questions related to webinar topic that would require a reply from a medical individual. Will they continue to respond to questions that were posted.

Posted Thu, Mar 24 at 6:08pm CDT

jbartelt

Jennifer Bartelt replied:

Yes, we are working to sort through all of the questions as some were answered during the webinar. You'll see the answers to your questions very soon. Thanks!

Posted Fri, Mar 25 at 8:37am CDT

phaun

phaun wrote:

I am signed up for the Wed. March 23 webinar on stem cell /osteoarthritis. There is a time conflict with an appointment I can't break. Is there a way to access the program? 

Posted Fri, Mar 18 at 11:14am CDT

The webinar is archived. You can watch it any time here: https://connect.mayoclinic.org/event/1001?instance=1&year=2016&month=3&day=23&view=

Posted Thu, Mar 24 at 9:57am CDT