My mom has been battling Melanoma for 7 years and was just diagnosed again with stage lll melanoma. She has two options from her specialist. Either take ipilimumab to possibly shrink the tumor before surgery or to just go through with the surgery and then take the ipilimumab. Would it be better to just get it out of the body all together or shrink it first? I know that air exposure can aide in the spreading process so would it matter if it's shrunk in size or not?