Ibrance and Liver Lesions: What's your experience?
Hi Folks, Just went on Ibrance (1 session so far and on my 2nd). Lesions in my liver are a tiny bit bigger in 2 months. I have been told they will get larger first and then start to get smaller. What's been your experience? Also, the nausea; has anyone had it both in the morning and at night? Thanks everyone!
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I agree with @mdr3 please call your doctor right away and ask them if his is normal. If there is a problem, it is better addressed before it becomes an emergency. I have heard tired is a thing but the breathing is a bit concerning.
I did call Dr office yesterday afternoon. Received call this morning from Dr. Office and nurse told me to stop the meds Ibrance and Letrozole until I am seen by the Dr. on Friday. Thanks for the concern.
Hi Everyone, I am new here. Been on Ibrance5 days and am having bad pain in my upper right abdomen and upper back all night long. Is this normal?? Is it just bone pain???
Welcome, @mglinkhart. I'm tagging a few other MBC folks who also have experience with Ibrance, like @mhsosa @eku @carbut58 @claudiamaria @hockeymom25 @elizm @trivia @pampurr. Hopefully they can share their experiences, especially when starting the drug.
@mglinkhart, you've been on the medication for just over a week now. Has the abdominal and back pain subsided? Did you report it to your oncologist or symptom management nurse? How are you doing?
I ended up
Switching g the times around for when I take my meds and it has helped. I take my Anastrozole in the morning and the Ibrance at dinner and it seems to even things out a bit. Even the nausea has lessened. Every day is a new challenge. Yesterday I woke with terrible headache in my eyes. To
Move my eye was so very painful lasted all day but I’m fine today. But I’m still here so hoping today will be a good day. Thank you for contacting me. It is very much appreciated.
Hi @mglinkhart, Unfortunately, Ibrance didn't work for me. After 2 months of being on it, the scan showed my liver tumors had increased exponentially. So I went on Piqray. That was over the course of a year. I had digestion issues and eventually my hair started falling out. I found out later I had Neuroendocrine Breast Cancer (rare) so these treatments didn't work. Sometimes, when you start a drug, if the tumors are dying, they expand slightly. That can cause pain. I would give it a few more weeks to be sure if its working and do a blood test with cancer markers.
Thank you for your thoughtful reply. I am sorry it didn’t work for you and I surely hope something else will.
Dr. Took me off of Ibrance. She now has me on Kosqali and anastrozole. But because I have such hard time accepting meds, she changed the prescription. Instead of taking three kisqali at once for three weeks. She now wants me to take one kisqali daily for two weeks, take a week break and then start again the process. I am continuing with the anastrozole daily. I don’t know what else she can have me try. Verzenio and Ibrance my body would not tolerate. I am also going to get the xgeva shot for the bones every six months. Receive The first shot in July. Zomeda really messed up my teeth. Any ideas or issues you see with my plan, please let me know. I had been in unbearable pain, especially my back. Dr recommended kypnoplasty surgery. I have to admit it helped a lot with the spine pain. Had surgery in June and so far my pain is no longer as immense as before surgery.
I have been on Ibrance 125 mg, and Lextrozole 2.5 mg for 2 years and I am in remission.