Hi, I am a middle age woman with more than 4 years of sleeping and waking up with severe tightness in my upper chest and jaw everyday. The feeling of heaviness in my upper chest subsides in about an hour after waking up. I have gone through tests for GERD and pulmonary conditions. No definitive diagnoses determined. I have also tried medications for GERD and take inhaler before sleep. Nothing worked. My GI doctor already gave up on me. I do have regurgitation of heart, but my Cardiologist confirmed that this is not heart related. I also do not have a diagnosis for my positive ANA and high Titer. Lately, I developed dull pain on the back of my head behind my ear. My Neurologist is not worrying about it and told me to go back for a follow-up in a year. My biggest problem is sleep and waking up with severe tightness in my upper chest. Is it stress related?