From what I understand, the symptoms experienced by N.M.O. Patients are similar to those experienced by M.S. patients, and Tonic Spasms are one of these symptoms. I never knew they were related until finding an article; relating Neuromyletis Optica with Tonic Spasms, and a Muscle relaxer is prescribed. Log onto the Institute of neurological disorder, and perform some research. Anyway I still suffer from them, and my neurologist states that she's willing to change my medication(Baclofen), and try something else to alleviate the pain of these horrible spasms. I would really like to believe, and know that I'am a survivor, and will outlive these symptoms until a cure is found. Please let me know of any long term survivors of NMO, and how they're dealing with existing conditions, and what medications they're taking. Life should go on with N.M.O., and be understood as a manageable condition. Thank you; Paubla "luckygirl"