Does anyone have experience with Mirtazapine?

Posted by faithshouse @faithshouse, Jun 20, 2019

My husband has trouble staying asleep, and falling back to sleep when he awakens during the night. It concerns him, but we wouldn’t say that he is depressed. He had heard about Mirtazapine for sleeping. His doctor prescribed 15 mg. Has anyone had side effects, or depression while taking Mirapine? Is it more for depression, than for sleeping? Thanks for your feedback.

@faithshouse

Glad it is working for you. It really wreaked havoc for my husband. He’s not taking anything now, and has been doing pretty well.
Good luck!

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@faithshouse – how is your husband doing lately? How about you?

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@gettingbetter75

So…update from me, I've been through the gamut this last month now that I'm fully off of Clonazepam. I've tried Remeron, Doxepin and Trazedon to help combat chronic insomnia and all of them worked initially but stopped working effectively after about 3 days. That's my personal experience with these, I understand this can be different for others. Not responding to medication is quite frustrating for chronic insomnia, in fact it's exhausting. I've finally been trying Gabapentin with good results so far, knock on wood. Does anyone else have experience with Gabapentin for insomnia?

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I have taken low dose mirtazapine for years for sleep, now the doc added melatonin for restless leg syndrome, started out with 7.5 then upped it because the lower dose has more side effects. Gabapentin worked for pain and migraines for a short time then you have to keep upping the dose but it is used for lots of things. I am very sensitive to meds so it is trial and error. I have an acoustic neuroma which makes me dizzy constantly with migraines and vertigo. Supposed to try one of the new injections but I am sooo tired of trying meds

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I have taken it for years for sleep and occasionally add a small amount of melatonin with it for restless leg syndrome. The doc told me the smaller the dose the more side effects and the higher the dose the less side effects but I stay at 15mg. Everything has side effects, ugh

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@sarasally2

I have taken it for years for sleep and occasionally add a small amount of melatonin with it for restless leg syndrome. The doc told me the smaller the dose the more side effects and the higher the dose the less side effects but I stay at 15mg. Everything has side effects, ugh

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That's a new one on me! Less is worse than more? I took Ambien for 18 years. Just switched to Lunesta and it works well.
Suncance(RB)

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I took mirtazapine for 3 – 4 a few months ago to see if it would help with my insomnia. I started with 7.5mg then upped to 15mg. Thankfully, it did not work. I say thankfully because the brain fog on this medication was quite substantial. I vaguely recall sitting through PowerPoint presentation with little to no memory of what was being communicated. If I had to guess, I would say my cognitive function was maybe 25 – 30%. Yep, pretty bad. Medications affect people differently but this my experience. No for me. I am not taking gabapentin to help with my insomnia, it's been the best one so far with the fewest side-effects. I only take one capsule which is 200mg with UNISOM and melatonin. It works most nights which is a huge win for me after going through almost a full month of maybe 45min – 1 hour of sleep per night. One of the worst experiences of my life.

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Here’s my routine: I was prescribed 30 mg. Mirtazapine. I take 15 an hour and a half before bed. If I wake up in the middle of the night, I take the other 15. Works every time.

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Good afternoon @gettingbetter75 I am so sorry to hear of your week of almost sleepless nights. That is so tough to deal with and can lead to more depression and anxiety.

It sounds like gabapentin is working for you. I don't quite understand why you are taking two different sleep medications in addition to the gabapentin. Were those prescribed for you? I am just not a pill take so I don't understand the dosages.

I suppose that you may know about setting a chime that rings when it is time to prepare for bed. For us that means, medications taken, the TV turned off, digital devices turned off and a few moments of quiet meditation that begins with something like, "May I have a restful sleep tonight. May I be safe and protected from inner and outer harm." It works and can be a great habit to acquire. Let me know that you are continuing to be successful or if you have additional inquiries. Chris

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So far so good here, Chris. Yep, I take 5mg Melatonin, 110mg x 2 Magnesium Glycinate, 1x200mg Gabapentin and 1/2 a Unisom Extra Strength tab. At this point, honestly, as long as I can sleep with minimal hangover the next day is all I care about. If I can sleep 5hrs, I'm good. My insomnia journey prior to this is not something I can afford to repeat. I'm not talking, oh a had a bad nights sleep for say a few nights. This was full-blown chronic insomnia that went on for a little over a month. I was losing my grip on reality.

I will be going to a sleep clinic next week to further discuss my insomnia and/or any amelioration I can make in this regard. As an extra FYI for you, all this started when I finished a long time relationship/prescription with anti-anxiety medication. My new doctor (we moved) would NOT continue to prescribe that for me. The anti-anxiety medication might not have been entirely helpful with anxiety per se but it was certainly effective for insomnia. Now that I am off anti-anxiety meds, I have no plans to return on that awful stuff. I do feel a little better, more alive when I can get some sleep, that is. My only significant health issue is my sleep. I need to figure this out long term and I can continue as I was and/or better.

I'm a 44yr old father of two with a full-time eng job, experiencing insomnia at this level is not something I can tolerate again. So going back to the above medication + supplements, I'm OK with that for now. I also use the headspace app to help lull me to sleep. It too is helpful.

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@artscaping

Good afternoon @gettingbetter75 I am so sorry to hear of your week of almost sleepless nights. That is so tough to deal with and can lead to more depression and anxiety.

It sounds like gabapentin is working for you. I don't quite understand why you are taking two different sleep medications in addition to the gabapentin. Were those prescribed for you? I am just not a pill take so I don't understand the dosages.

I suppose that you may know about setting a chime that rings when it is time to prepare for bed. For us that means, medications taken, the TV turned off, digital devices turned off and a few moments of quiet meditation that begins with something like, "May I have a restful sleep tonight. May I be safe and protected from inner and outer harm." It works and can be a great habit to acquire. Let me know that you are continuing to be successful or if you have additional inquiries. Chris

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@artscaping Chris, can I presume that you retire at the same time every night? Probably a good idea but it just wouldn’t work for me.
I too go through periods of sleepless nights. When I have had 2 or 3 in a row I will take an small dose lorazepam (Ativan).it generally gives me just enough help. It’s not meant as a sleeping pill, it’s for anxiety, but when I’m not sleeping it is generally from anxiety.
JK

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Hi there @contentandwell,

The answer is yes, we do try to have a pretty normal routine. Doing so sort of creates a rhythm of life. I am trying to be predictable, e.g. meds at the same times, yoga at the same time, etc. Of course, you know what gets me off track….yep, it is reading and responding to Mayo Connect posts.

I did find that when I stayed awake too long for a few nights, it was harder to fall asleep and/or I was nodding off in the afternoon. Besides, my chipmunk family will come and chirp under the bedroom window if I haven't gotten up to feed them.

I do have to lollygag in bed a bit in the morning or at least until my legs tell me that they won't give out on me when I get up. Sometimes they just refuse to work well and I have to give them a few hours off.

Be safe and protected tonight. Chris

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@gettingbetter75

So far so good here, Chris. Yep, I take 5mg Melatonin, 110mg x 2 Magnesium Glycinate, 1x200mg Gabapentin and 1/2 a Unisom Extra Strength tab. At this point, honestly, as long as I can sleep with minimal hangover the next day is all I care about. If I can sleep 5hrs, I'm good. My insomnia journey prior to this is not something I can afford to repeat. I'm not talking, oh a had a bad nights sleep for say a few nights. This was full-blown chronic insomnia that went on for a little over a month. I was losing my grip on reality.

I will be going to a sleep clinic next week to further discuss my insomnia and/or any amelioration I can make in this regard. As an extra FYI for you, all this started when I finished a long time relationship/prescription with anti-anxiety medication. My new doctor (we moved) would NOT continue to prescribe that for me. The anti-anxiety medication might not have been entirely helpful with anxiety per se but it was certainly effective for insomnia. Now that I am off anti-anxiety meds, I have no plans to return on that awful stuff. I do feel a little better, more alive when I can get some sleep, that is. My only significant health issue is my sleep. I need to figure this out long term and I can continue as I was and/or better.

I'm a 44yr old father of two with a full-time eng job, experiencing insomnia at this level is not something I can tolerate again. So going back to the above medication + supplements, I'm OK with that for now. I also use the headspace app to help lull me to sleep. It too is helpful.

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@gettingbetter75, Good evening. I understand now. Thanks for the clarification. I was just being a bit of a worry wort. I do want to share with you the reason for my concern.

My life partner is a widower. His wife was killed by a young man on drugs. He thought he was doing quite well, back at work, gathering and sorting belongings, trying to move on with his life. He was a counselor and therapist in a mental hospital for several years. His insomnia just hung on like a dark cloud to the point where he did lose his grip on reality and ended up as a patient at the very same hospital where he had worked. With special care and some great talk therapy, he learned to work his way through the grieving and towards acceptance.

So please be safe and protected from inner and outer harm today. Chris

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@artscaping

Hi there @contentandwell,

The answer is yes, we do try to have a pretty normal routine. Doing so sort of creates a rhythm of life. I am trying to be predictable, e.g. meds at the same times, yoga at the same time, etc. Of course, you know what gets me off track….yep, it is reading and responding to Mayo Connect posts.

I did find that when I stayed awake too long for a few nights, it was harder to fall asleep and/or I was nodding off in the afternoon. Besides, my chipmunk family will come and chirp under the bedroom window if I haven't gotten up to feed them.

I do have to lollygag in bed a bit in the morning or at least until my legs tell me that they won't give out on me when I get up. Sometimes they just refuse to work well and I have to give them a few hours off.

Be safe and protected tonight. Chris

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@artscaping Chris, I consider it a major accomplishment that we are now generally eating dinner at around 6:30 every night. It had gradually crept up to eating at around 8:00, definitely too late. It does sometimes go to 7:00 now but that's on the edge of acceptable. My femur fracture has really set things off too. I had been getting up at a pretty regular time in the morning, about 7:30 or sometimes 6:30 to get to my health club, etc., but now since I am not going I sleep late a lot. I am thinking of resuming my membership in the next week and just go to the gym for upper body exercise. Honestly though, my leg is still really quite painful. I have been very conservative in my use of Tramadol, which has helped in the morning, but I am about to run out. I doubt the doctor will prescribe it again, they really err on the side of caution with the opioid epidemic.
JK

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