My wife, who is 79, was diagnosed with dementia about 2 1/2 years ago. It's progressed quite a bit. She has been on 40mg of Omeprazole (Nexium) for about 4 or 5 years, for reflux. I was wondering if anyone else has had a similar problem? The Doctors have had her on arricept, aggrenox, 600 g of calcium (twice a day), vitamin D3 and Lisinapril. He also put her on Namenda but I took her off of it when she seemed to be getting more confused, until I can talk to the doctor. Sometimes I wish I could take her off of everything and start all over.