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I'm 54 years old and I'm ill with essential thrombocythemia Jak2 and platelets are more than 700,000 .I ask if in this condition I can be vaccinated with the Covid19 vaccine knowing that the vaccine has thrombophilic properties?
Interested in more discussions like this? Go to the Blood Cancers & Disorders group.
Hello, and welcome to the Mayo Connect community. We are people living with a wide variety of diseases and conditions, who try to help one another along the way. We each strive to be informed medical consumers, and our own best advocates in our care. We are not medical professionals, so not able to provide medical advice. We can tell you what has worked for us (or not) and provide you with information and conversation about your question.
This is a question for the physician who manages your condition, who at this point should have some insight into whether you can safely be vaccinated, and whether there is a specific one offering less chance of side effects.
Hi @zeffirino, welcome to Mayo Clinic Connect. I've added your question to the Blood Cancers & Disorders group https://connect.mayoclinic.org/group/blood-cancers-disorders/
Here you will meet other members talking about essential thrombocythemia and JAK2. In particular, I invite you to see these discussions:
– Effect of COVID vaccine on JAK2 MPN https://connect.mayoclinic.org/discussion/effect-of-moderna-vaccine-on-jak-2-mpn/
– Side Effects Of Hydrea or Hydroxyurea for ET https://connect.mayoclinic.org/discussion/side-effects-of-hydroxyurea-et/
– JAK2 ASXL1 Mutations: Anyone else? https://connect.mayoclinic.org/discussion/mutations/
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Thank you for answering I was hoping to be able to comunicate with a person who has my disease and who had done the vaccine.My doctor is not exhaustive on this subject and this is the reason why I seek other opinions and other experiences.
I am considering a monoclonal antibody trial vaccine versus the viral vector and mRNA vaccines out. I have family with JAK2, mine is negative but PLTs tend to run on high side and I have MGUS. I am trying to do a lot of research on it and asking the researchers questions about it before I consent. I’ve asked on this forum today if anyone has entered this trial for what seems to be a safer alternative. Maybe your hematologist can weigh in if he thinks a monoclonal antibody vaccine trial enrollment is a good option for you.
Can you share a link to this trial vaccine? I'm sure many would be interested to read about it. Thank you.
Hi Stillwell, are you referring to the emergency use authorization (EUA) for REGEN-COV (casirivimab and imdevimab, administered together)? This monoclonal antibody therapy is for adults and children over 12 who are at high-risk of hospitalization or death after a known exposure to someone with COVID-19.
The FDA states that:
"Prophylaxis with REGEN-COV is not a substitute for vaccination against COVID-19. FDA has authorized three vaccines to prevent COVID-19 and serious clinical outcomes caused by COVID-19, including hospitalization and death. FDA urges you to get vaccinated, if you are eligible."
Here's more information:
– FDA authorizes REGEN-COV monoclonal antibody therapy for post-exposure prophylaxis (prevention) for COVID-19 https://www.fda.gov/drugs/drug-safety-and-availability/fda-authorizes-regen-cov-monoclonal-antibody-therapy-post-exposure-prophylaxis-prevention-covid-19
It doesn't look like an either one or the other situation. Good for you for doing your research.
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