I am a healthy 34 yr old woman, and have been suffering from chronic leukopenia and neutropenia for the past 3-4 yrs. I have been referred to numerous specialists, whom almost always refer me to Mayo Clinic after 4 appointments. All blood work shows neutrophils between 0.8-3.1 WBC, neutrophils are often low and lymphocytes high. Three penacillin-based antibiotic trials (7-11 days) demonstrated marked improvement of WBC to 4.7-5.4, but WBC was again low after 2 weeks post therapy. All tests are negative, with the exception of Brucellosis IGM positivity, yet Agglutination tests for brucella within normal range 1:40. Seeking a diagnosis. Please comment with ideas or any help.