My blood work came back positive for ANA. What is ICAP nomenclature: AC-25,26 for spindle apparatus pattern?
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Here is an article on the patterns for ANA: http://www.rapidtest.com/pdf/ANA_HEP-2_IFA_230512DE%281-3-2014%29.pdf#:~:text=Spindle%20fiber%20pattern%2C%20chromosome-positive%3A%20The%20spindle%20fiber%20pattern,appearance%20extending%20from%20the%20centriole%20to%20the%20centromeres.
And an excerpt on the spindle pattern:
Spindle fiber pattern, chromosome-positive: The spindle fiber pattern is
unique to cells undergoing mitosis where only the spindle apparatus fluoresces. This pattern has a “spider web” appearance extending from the centriole to the centromeres. The pattern is suggestive of autoantibodies to the microtubules and its significance is unclear; however, an association between the spindle fiber pattern and carpal tunnel syndrome has been suggested.
An ANA of 1:160 is relatively low and some healthy people have that, according to my doc. Do you have symptoms? Do you have carpal tunnel?
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No, I don't have any symptoms of carpal tunnel. I have extreme fatigue, muscle and joint pain with stiffness. Recent episodes of dizziness, headaches.
@crumly71 Hi and welcome to Mayo Clinic Connect! Unfortunately, no one at MCC is a health professional so we are unable to comment on your lab values.
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