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Do Prolia injections affect the kidneys?

Osteoporosis & Bone Health | Last Active: Nov 14, 2023 | Replies (85)

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@peggydenmon

Hi trinity. I also live in the armpit of Pa. I wonder if it is the same armpit. I started on Prolia and am due for my 4th shot this Thursday. I got the results from my blood work and was shocked with the GFR number. It does make me wonder if it's worth it. I've been relatively healthy my whole life and I don't want to "kill" my kidneys. Actonel didn't help and I was on that for 10 years. I'm really considering stopping the shot to save my kidneys. Although what alternatives work to improve the bones? Have you found out any more options?

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Replies to "Hi trinity. I also live in the armpit of Pa. I wonder if it is the..."

Hi Peggy! I live in the village of Wilcox, PA..It is considered NW PA. As you have reviewed my postings, 1 PROLIA INJECTION AND MY GFR PLUMMETED 12 POINTS...My second one was on 3/25....If labs were done prior to the injection and I reviewed them, I would have definitely opted out! !!! I am supposed to have both PTH AND GFR repeated...I still waiting for the order from my rheumatologist. ..I thought midway about 3 months to check the values....I AM DONE WITH PROLIA...I am 67 years old and a retired Director of Nursing...I have also contacted the FDA RELATED TO THIS...PLEASE CHECK YOUR GFR VALUES DURING YOUR COURSE OF PROLIA TREATMENT...IF IT HAS BEEN A CONTINUOUS DECLINE YOU INDEED HAVE SOMETHING TO REPORT....SOUNDS like you are otherwise healthy...Please keep me apprised of progress...Oh, first I started with BONIVA for about 10 years; my stomach was horrible...I had such GI DISTRESS...NEXT was RECLAST...I had a total of 3 infusions...Insurance dictated no further payment or recommendation...Then last year I decided to see a rheumatologist again...Hence PROLIA...My DEXA SCAN IS DONE EVERY OTHER YEAR PER MEDICARE...IN MY age bracket, the bone changes are slower in degeneration now..I WILL continue to walk daily and be active...U have always walked 5 miles daily...I will post after my labs; however, none of us are thrilled to enter the hospital setting for labs due to the COVID 19...I have seen other declines in GFR ON THIS MAYO CLINIC SITE...We as a group need to report negative findings to both the FDA AND PROLIA FOR THEIR ADVERSE REACTIONS. ..KEEP IN TOUCH AND THANK YOU SO MUCH PEGGY...