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HER2- and ER/PR+

Breast Cancer | Last Active: Jan 30, 2023 | Replies (69)

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@callalloo

I asked Exact Sciences about the risk of 'spread' versus recurrence since the OncotypeDX (the test I had) doesn't specifically predict that. The answer is interesting and the person in the science section whom I spoke with is sending me more info. But, basically, the same TaylorRX data pool from which Oncotype based much of its algorithm (not a good explanation but to keep things simple) also included 'spread' as well as recurrence statistics. Inferentially, a low risk of distant recurrence correlates with, also, a low risk for spread from cancer site assuming clean margins. Cancer-free lymph nodes lowers that risk further. If only we could get 100% perfect data, decisions would be so much easier, sigh. But at least we have better tools than women even 20 years ago.

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Replies to "I asked Exact Sciences about the risk of 'spread' versus recurrence since the OncotypeDX (the test..."

Thank you.

Could you explain the difference between 'spread' and distant recurrence? I'm puzzled since if the bc is found elsewhere (distant recurrence) doesn't that mean it has spread? Thanks!