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Elevated liver enzymes post liver transplant

Transplants | Last Active: Aug 26, 2022 | Replies (10)

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@hello1234

Hi @crystalfaye 😊
I am a two year post kidney transplant patient. Pre-transplant, I never had elevated liver enzymes or any liver issues. But after starting the immune suppression drugs, my liver enzymes became elevated and stayed there until the following year when my Cellcept dosage was reduced in half. After the reduction, the enzymes stayed elevated, but they were now in the high normal range. And now, a year later after the Cellcept was reduced, the numbers are back in the low normal range. I am a kidney transplant patient, not a liver transplant patient, so of course your doctor will be the best source. Are you taking Cellcept and Tacronlimis? Are you also taking drugs like Bactrin? I have learned that these medications can all cause elevated liver enzymes however in the early months after transplant, they sometimes make the decision to put up with the elevated liver enzymes. They reduced my Bactrin first to Monday, Wednesday, Friday instead of every day. That had a small minimal effect. It was the Cellcept that needed to be reduced. Is it possible that your elevated enzymes are caused by the meds too?

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Replies to "Hi @crystalfaye 😊 I am a two year post kidney transplant patient. Pre-transplant, I never had..."

Hello and thank you for your response. 😊 I was on Bactrin until about four weeks ago. The surgeon felt that is was affecting my potassium levels. He changed it to this yellow liquid stuff called Atovaquone and my level went back to normal.

I had my clini appointment today and the surgeon saw lowered my Celcept. We’ll see how that affects my blood work.

In the meantime I am being scheduled for an MRI of the stomach to rule out a bile duct restriction.

Are you having any additional issues since your transplant? Are you able to return to your normal routine?