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Will med-induced glomerular filtration rate (GFR) rebound?
Kidney & Bladder | Last Active: Aug 23, 2022 | Replies (11)Comment receiving replies
@mjsmayo Welcome to Mayo Clinic Connect!
You are asking about a "rebound" in your eGFR after stopping hydrochlorothiazide. That remains to be seen, honestly. There are several factors that can influence the reading, including but not limited to the following: your hydration level at time of blood draw, time of day, recent activity, weather, additional medications recent meals.
You will find that the majority of medical doctors will look at a trend of your blood results, not a single value. When do you have your next set of labs scheduled? Was it your doctor who stopped this new medication; what was his reasoning for starting it, then stopping it? What did he replace it with, if anything?
If you care to share a bit more about your kidney disease, the cause of it and how long you have been on this journey, I am happy to answer any questions you have!
Ginger
Replies to "@mjsmayo Welcome to Mayo Clinic Connect! You are asking about a "rebound" in your eGFR after..."
Hello again :
I plan to schedule another lab draw a week or so after I stop this new medication
Actually, I can’t be sure that the decrease in EGFR is because of the new medication hydrochlorothiazide since there is a month between my lab draws. I am only guessing that is the reason in that the gfr went down so much so quickly and the new medication is the only change that was made in my life during that time period.
I will know more when I stop taking the medication and do another blood draw.
Ginger, thanks for the helpful information. Regarding factors that may affect eGFR testing results, how do that affect it? Is it better to be well-hydrated at the time of the test? Better or best time of the day of the test? More activity or less prior to test? Maybe wait to take meds until after test? Not eat at all or not eat certain things. Just wondering. Thanks.
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Hi Ginger:
The reason my doctor started this medication is because my blood pressure reaches over 140 sometimes although half the time it is in the 120 and 130 range. It appears that the doctor wants my blood pressure to be below 140 at all times. I have been taking nifedipine for over 30 years.
I started this new medication on 7/29 and had a blood draw on 8/5. That’s when I discovered that my eGFR went from 53 to 42. My creatinine has also increased. My potassium went down but glucose went up.
On top of all these problems, I have a rash on my face with blisters even though I apply SPF 55 sunscreen daily.
I have informed my doctor of all these problems as well as photos of my face with rash and blisters. She is aware that I do not want to continue with this medication. I am awaiting her reply.