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Possible/Pseudo Cushing syndrome

Diabetes & Endocrine System | Last Active: Feb 19 7:27pm | Replies (24)

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@pinkrosebud

Does anyone here have a diagnosis of Pseudo Cushing’s? I was diagnosed with Polycystic Ovarian Syndrome and T2D, but I have elevated cortisol levels in blood, 24 hour urines, and midnight salivas. I have normal ACTH levels, I suppress on dexamethasone, normal pituitary MRI and normal abdominal CT scan. I also took the DDAVP stim test, which was normal. I haven’t met a lot of people with Pseudo Cushing’s. I’m not a drinker, in fact i don’t drink at all. I do have OCD and wonder if that is where my HPA axis dysregulation stems from. Being a case of pseudo, no endocrinologist has really been able to offer me a solution to regulate this imbalance and living with this is making it very difficult to balance my PCOS, weight, and glucose levels. I also have elevated prolactin, but again no pituitary tumor behind the cause. It’s idiopathic. Anyone else in a similar situation? It seems pretty rare, but maybe it’s not, maybe it’s simply under reported or diagnosed?

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Replies to "Does anyone here have a diagnosis of Pseudo Cushing’s? I was diagnosed with Polycystic Ovarian Syndrome..."

@pinkrosebud, I'd like to bring @astaingegerdm and @jmb73 into this discussion and hopefully to add some thoughts to your post. What a relief that you do not have a pituitary tumor, but frustrating that you, as yet, have no plan of action to help regulate the imbalances.

Have you considered getting a second opinion at a large medical center like Mayo?

Consider looking into Cyclical Cushing's. It is nightmare to diagnose though but hair testing is the most promising method.