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crustycat (@crustycat)

Glucose Spikes and Small Fiber Neuropathy Flare-ups

Neuropathy | Last Active: Nov 22, 2021 | Replies (5)

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Hello @crustycat, Welcome to Connect. There are other members who have had similar experiences with sugar. @tdemaria and @sherlock have discussed sugar and neuropathy flares in another discussion and may have information to share with you. Also, @jenniferhunter shared some suggestions in the older discussion you may find helpful – https://connect.mayoclinic.org/comment/234391/

Since you mentioned you have Type 2 Diabetes, you might find the following discussion beneficial. @kbart posted that it helped reverse type 2 diabetes – https://connect.mayoclinic.org/comment/336062/:
— Low-carb healthy fat living. Intermittent fasting. What’s your why?: https://connect.mayoclinic.org/discussion/low-carb-healthy-fat-living-intermittent-fasting-whats-your-why/

Do you mind sharing how long you have been diagnosed with small fiber neuropathy and how long you have had diabetes?

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Replies to "Hello @crustycat, Welcome to Connect. There are other members who have had similar experiences with sugar...."

Thank you @johnbishop, I was diagnosed with SFN this past February, but have had the symptoms much longer. I have been chasing this for a number of years. Eventually had to go out of town to a different neurologist that quickly suspected SFN and a subsequent skin biopsy confirmed it.

I had a life threatening illness in 1999 and was given high doses of steroids and doctors suspect that was what caused the onset of my T2 diabetes. Unfortunately, I didn't heed the warnings and change my eating habits, etc. I spent many years gaining weight and diabetes worsened. At my worst, my weight was nearly 270 and A1C had reached 11.6. In 2017, I made a concerted effort to lose weight and my dropped 60 pounds. I really need to lose an additional 30-40 pounds but that will be difficult.

The good news is that I have gotten the blood glucose under control (as long as I behave) and have been able to reduce my diabetes meds substantially.

Unfortunately, my lifestyle choices took their toll and have left me with SFN. I have moderate long nerve fiber neuropathy, but not very bad.

I am currently treating SFN symptoms with pregabalin, oxcarbazepine, and tramadol. The tramadol is a recent addition and is not one that either my doc or I really desire, but it really does take the edge off in the evenings when my SFN seems to flare up the most.

I will take a look at the suggested links.

Thanks again for your prompt response.


I was diagnosed with Type 2 about 6 years ago. I took medication for a little over a year then began the Wheat Belly diet. No grains and no sugar. My A1C returned to normal levels.