Please be careful! I can only share my own terrible experience. I'd been on Prolia several years and because of a change of doctors (one retired) my shot was a few weeks late. During that time three vertebrae broke leaving me in constant pain and unable to resume many normal activities, travel, etc. But because I am ON Prolia I have macular degeneration in BOTH eyes requiring treatment by a retinal specialist – which includes periodic shots IN the eye! I wish that I had never gone near Prolia!