Kidney Disease Cure: What's the latest?

Posted by mikek206 @mikek206, Jul 23, 2021

I read An article a few years back saying...A university in California has produced a compound that stops Kidney progression in its Tracks...What Ever Happened to that..? Did some big Pharmacal Company buy it and put it on the shelf for Money...

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@mikek206

Thanks, John...That's the one...some big Pharmaceutical Company has that info in a file cabinet somewhere...they don't want to cure anything...(no Money in it) all they are looking for are treatments to keep us coming back for more...Pop a Pill every days...keep them coming back...!

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@mikek206 I wouldn't be so quick to assume that someone is purposefully hiding a cure. Researchers work hard to find treatments that work. As I mentioned earlier, we hear about the promise of potential treatments in traditional media when research is in its earliest stages. Furthermore, the media like to use misleading headlines that proclaim a cure.

Note that in the article to which you refer (https://www.broadinstitute.org/news/new-compound-stops-progressive-kidney-disease-its-tracks), the research to date has only been done on animals. In this case, rats. In other words, very early in the research process.

It takes years for a treatment to get through all the stages of clinical trials and then approval for use. It is frequently stated that it takes an average of 17 years for research evidence to reach clinical practice. Many promising treatments fail when progressing from animal trials to human trials, and researchers have to go back to the drawing board, so to speak.

I look forward to seeing the development of this promising trial. But please note that it is NOT a cure, but has the potential to slow the progression of some types of kidney disease.

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@colleenyoung

@mikek206 I wouldn't be so quick to assume that someone is purposefully hiding a cure. Researchers work hard to find treatments that work. As I mentioned earlier, we hear about the promise of potential treatments in traditional media when research is in its earliest stages. Furthermore, the media like to use misleading headlines that proclaim a cure.

Note that in the article to which you refer (https://www.broadinstitute.org/news/new-compound-stops-progressive-kidney-disease-its-tracks), the research to date has only been done on animals. In this case, rats. In other words, very early in the research process.

It takes years for a treatment to get through all the stages of clinical trials and then approval for use. It is frequently stated that it takes an average of 17 years for research evidence to reach clinical practice. Many promising treatments fail when progressing from animal trials to human trials, and researchers have to go back to the drawing board, so to speak.

I look forward to seeing the development of this promising trial. But please note that it is NOT a cure, but has the potential to slow the progression of some types of kidney disease.

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I know this is not a cure...If it was it would never hit the Market...That's How much trust I have in Big Pharmaceutical Companies...

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@mikek206

Well, I have Kidney disease since 2001...went through 2 doctors...All they know is telling you you have to think about Dialysis...I did tell them No...I'm at 15% and it seems to be holding at that... feel fine with no problems as yet...No high blood pressure & no diabetes.. got this problem from dehydration...funny all these years and nobody has anything for this...Very Funny...

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I read where unless you feel like crap, try to stay off dialysis and cotrol the symptoms with medication until you are 10 and under. Your body knows.

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@czsalt64

I read where unless you feel like crap, try to stay off dialysis and cotrol the symptoms with medication until you are 10 and under. Your body knows.

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Trying Very Hard To Do Just That...Thanks...

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Just read an article that the government has been giving Texas Grants since 1995 to solve End-Stage Renal Disease Facility in Texas...Come on Since 1995...What Have They Done With All That Money?

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I think this might be what you are referring to Mike.

The Texas End Stage Renal Disease Facility Licensing Act was first enacted in 1995 by the 74th Legislature. HHSC develops rules that establish minimum standards for ESRD licensing procedures; for granting, denying, suspending, and revoking a license; for licensing fees; for operation; and for requirements concerning design, construction.
https://www.hhs.texas.gov/providers/health-care-facilities-regulation/end-stage-renal-disease-facilities

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@colleenyoung

I think this might be what you are referring to Mike.

The Texas End Stage Renal Disease Facility Licensing Act was first enacted in 1995 by the 74th Legislature. HHSC develops rules that establish minimum standards for ESRD licensing procedures; for granting, denying, suspending, and revoking a license; for licensing fees; for operation; and for requirements concerning design, construction.
https://www.hhs.texas.gov/providers/health-care-facilities-regulation/end-stage-renal-disease-facilities

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I still would like to know Where Is Money Going...?

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I recently saw on Good Morning America that a few scientists had genetically modified a pig kidney for transplant into humans. According to the program the study looks promising. How ever I am an animal rights supporter so I want to know what happened to the pig?

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@czsalt64

I read where unless you feel like crap, try to stay off dialysis and cotrol the symptoms with medication until you are 10 and under. Your body knows.

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That's my goal. EGFR between 12 and 15 for almost 10 years now. Managing to avoid dialysis so far, although had to switch nephrologists until I found one that was willing to let me try to go without dialysis. Not easy to figure out how to get enough electrolytes to stay alive but not too much. Spent one night in the emergency room for hyperkalemia but so far guessing and experimenting and researching nutrition content of everything I eat has worked.

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@codered032

I recently saw on Good Morning America that a few scientists had genetically modified a pig kidney for transplant into humans. According to the program the study looks promising. How ever I am an animal rights supporter so I want to know what happened to the pig?

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Since pigs are like humans, it only needs 1 kidney to survive. Maybe the pig is an altruistic living donor and is just fine. If so, more people should be like this pig!

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