Sue, thank you for your reply. First, I should say my memory is really messing with me. I checked my little med notebook to see when I started taking the mag, and remembered that it was likely that a new scrip for Cytomel, on top of my usual Synthroid, had triggered the weight loss. How could I forget that? The Cytomel plus a single Citalopram for my bipolar, dredged up after I'd discontinued them as unnecessary, but popped one for anxiety (stupid, I now know) precipitated the high BP ER trip, they said at the ER. Then the digestive probs took over and have caused continued weight loss. The magnesium supplement I take (Mg Bright) is poorly labeled, but apparently is malate, not citrate. I take no more than the RDA, and it doesn't put a dent in the constipation. I do think it is ameliorating the high BP, but I could be wrong. It is supposed to be a relaxing sleep enhancer also, another reason I am taking it. But your comment has caused me to realize I need to be more careful. Going back in person to the N.P. is a tricky option these days, but calling her would make sense. Thanks for the sound advice. I will transfer this gut problem to the digestive problem discussion, since that is its main thrust. Glad I found Mayo Connect. Such very good people here.