@joanden Tired, yes – the heavy load of antibiotics can make you feel quite tired. Fever, I'm not so sure – what about anyone else? Is this a side effect of any of the Big 3? I already had a fever at the beginning of my therapy and it gradually subsided after about a month. Also, as the therapy progressed, I had increasing gastro symptoms – be sure you are eating food with good live cultures, and/or taking a good probiotic to keep your intestinal flora replenished. Also, although theses are strange and stressful times, be sure to line up opthalmology and audio appointments to be sure the drugs are not causing eye or hearing problems. Did your physician have you get baseline checks done before you started?