@karen00 As you read the reply from @elmay you may find some tips to help you. Each person has their own best way to deal with a sudden change in meds or our environment. This is my first winter in a new state, where there is a definite seasonal change. I find myself in sweats a lot of the time, and moving slowly, but forcing myself to move. I know it will make me feel better even if my body and mind complain at the time ;)) I have set small goals to accomplish, nothing major, so that getting those done make me feel like something was accomplished. It can be a struggle to get through each day. So try for getting through the next few hours, then repeat. I treat myself to a nice cup of tea each night, as a ritual that then I can rest. Is your new pain medication in response to a new issue, or a change? What will you do for yourself today?