@blue99 and @kleelibby I have had the same problem as you two. I have finally found a doctor who has been able to help me. He stuck with me and saw that I got the right meds. Some people are immune to certain SSRI's due to a gene. Then there are people like me that do not digest the meds well. The older we get the more inefficient our digestive systems get. Thus older people may need a larger dosage. I take about 3 times the normal amount. If your doctors are not helping then find one who is willing to keep on trying until they find the answer. Keep us informed in your progress. We care for people here.