Dropping PSA score with Gleason score of 7

Posted by cayandray @cayandray, Sep 3, 2017

How can a PSA drop with a Gleason score of 7? The biopsy showed that the cancer had attacked the nerves. Should I consider monitor with this situation?

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Hi Cayandray,
Good question regarding the relationship between PSA and Gleason score. I’m tagging fellow members @predictable @6608 @hamhock @gmack @bboxer @philn @flor @ronoir @donnelson @oldkarl to see what they may add this conversation.

You may also be interested in joining these discussions on Connect:

– prostate cancer treatment choices http://mayocl.in/2uqQ5YN
– Prostate cancer treated with Leuprolide http://mayocl.in/2uqJJIY
- Why did you choose brachytherapy for prostate cancer https://connect.mayoclinic.org/discussion/why-did-you-choose-brachytherapy-for-prostate-cancer/

@cayandray Have you had any treatment for prostate cancer or have been on active surveillance (Watch and Wait)?

REPLY
@colleenyoung

Hi Cayandray,
Good question regarding the relationship between PSA and Gleason score. I’m tagging fellow members @predictable @6608 @hamhock @gmack @bboxer @philn @flor @ronoir @donnelson @oldkarl to see what they may add this conversation.

You may also be interested in joining these discussions on Connect:

– prostate cancer treatment choices http://mayocl.in/2uqQ5YN
– Prostate cancer treated with Leuprolide http://mayocl.in/2uqJJIY
- Why did you choose brachytherapy for prostate cancer https://connect.mayoclinic.org/discussion/why-did-you-choose-brachytherapy-for-prostate-cancer/

@cayandray Have you had any treatment for prostate cancer or have been on active surveillance (Watch and Wait)?

Jump to this post

You need to understand that the Gleason score actually has little to do with how serious the cancer is. I also have my own Gleason score of Seven, since 2012. Seven is the total of two scores, a three and a four, or a four and a three. All that these really mean is that there is a different variety of options for the PT and the Uro to take their pick from. My PERSONAL choice was 1. Surgery of some kind. 2. Radiation of some kind, especially Proton Beam. 3. Hormone shots every month to six months. 4. Watch and wait. My URO chose a year between shots. He said I was too fat to do the surgery bit. He said OK to the proton beam, but that radiation oncologist quit and moved to another country. He started with the shots every three months, then 6, and then a year. Finally, He really went off the track, and said we would just watch and wait. I would have changed UROs again, but my previous URO just wanted to prove his presence in the LGBTQx community. About then, the thing about Amyloidosis reared its ugly head, so I am watching and waiting. WATCHING the world go by and my money go out the window, and WAITING to die. All the docs agree that I have less than two years to go. By the way, my PSA is now approaching 20.

REPLY
@colleenyoung

Hi Cayandray,
Good question regarding the relationship between PSA and Gleason score. I’m tagging fellow members @predictable @6608 @hamhock @gmack @bboxer @philn @flor @ronoir @donnelson @oldkarl to see what they may add this conversation.

You may also be interested in joining these discussions on Connect:

– prostate cancer treatment choices http://mayocl.in/2uqQ5YN
– Prostate cancer treated with Leuprolide http://mayocl.in/2uqJJIY
- Why did you choose brachytherapy for prostate cancer https://connect.mayoclinic.org/discussion/why-did-you-choose-brachytherapy-for-prostate-cancer/

@cayandray Have you had any treatment for prostate cancer or have been on active surveillance (Watch and Wait)?

Jump to this post

Thank you very much for your reply. It helps me understand everything.
I am very sorry about your Amyloidosis. I don't know anything about it but looked it up on the internet.
Ray

REPLY
@oldkarl

You need to understand that the Gleason score actually has little to do with how serious the cancer is. I also have my own Gleason score of Seven, since 2012. Seven is the total of two scores, a three and a four, or a four and a three. All that these really mean is that there is a different variety of options for the PT and the Uro to take their pick from. My PERSONAL choice was 1. Surgery of some kind. 2. Radiation of some kind, especially Proton Beam. 3. Hormone shots every month to six months. 4. Watch and wait. My URO chose a year between shots. He said I was too fat to do the surgery bit. He said OK to the proton beam, but that radiation oncologist quit and moved to another country. He started with the shots every three months, then 6, and then a year. Finally, He really went off the track, and said we would just watch and wait. I would have changed UROs again, but my previous URO just wanted to prove his presence in the LGBTQx community. About then, the thing about Amyloidosis reared its ugly head, so I am watching and waiting. WATCHING the world go by and my money go out the window, and WAITING to die. All the docs agree that I have less than two years to go. By the way, my PSA is now approaching 20.

Jump to this post

Hi. I am sorry to learn of the hitches and complications you have experienced in your treatment. If the P Ca has not metastasized, in view of the co-morbidity have you examined the alternative of focal treatment or of participating in ongoing trials of immunotherapy?

REPLY
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